Objective To investigate the relationship between neonatal retinal hemorrhage(RH)and changes in um-bilical artery blood gas indexes.Methods 596 newborns born in the obstetrics department of our hospital from May 2018 to December 2021 with retinal screening were selected and divided into bleeding group(n=230)and control group(n=366)according to whether the newborn had retinal hemorrhage,and could be divided into first-degree group(n=95),second-degree group(n=75)and third-degree group(n=60)according to the degree of bleeding.The hydrogen ion concentration index(pH),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2)and residual base(BE)of umbilical artery blood gas indexes,arterial partial pressure of carbon dioxide(PaO2)and resid-ual base(BE)values of neonates in the bleeding group and the control group and the Ⅰ.,Ⅱ.,and Ⅲ.groups were com-pared,and the relevant factors affecting the occurrence of RH were analyzed by logistic regression model,and the pre-dictive value of umbilical artery blood gas indexes on RH was analyzed by using the subject's working characteristic curve(ROC).Results The pH,PaO2 and BE values of the bleeding group were significantly lower than those in the control group,while the PaCO2 values were higher than those in the control group(P＜0.05).With the increase of the degree of retinal hemorrhage,pH,PaO2 and BE decreased,and PaCO2 levels increased,and the difference was statistical-ly significant(P＜0.05).The proportion of maternal diabetes mellitus,gestational hypertension,vaginal delivery,for-ceps delivery,emergency delivery,premature infants and newborns with a history of asphyxia in the bleeding group was higher than that in the control group(P＜0.05).The multivariate logistic regression analysis model showed that pre-term infants,maternal hypertension during pregnancy,maternal vaginal delivery,neonatal history of asphyxia,high level of PaCO2,low level of PaO2,BE and pH in umbilical artery blood gas were all risk factors for RH(P＜0.05).ROC curve analysis showed that the AUC of pH,PaO2,PaCO2 and BE predicted by RH was 0.755,0.719,0.669 and 0.816,and pH and BE were more predictive than PaO2 and PaCO2(P＜0.05).Conclusion Neonatal umbilical artery blood gas index is closely related to the occurrence and development of RH,and has certain reference value for RH screening,a-mong which pH value and BE value are higher.
newbornretinal hemorrhageumbilical artery blood gas analysiscorrelation
NETL
NSTL
维普
万方数据
