首页|三维心脏超声联合心电图特征对肺动脉高压患者心功能损害的诊断价值

三维心脏超声联合心电图特征对肺动脉高压患者心功能损害的诊断价值

Diagnostic value of three-dimensional echocardiography combined with electrocardiogram characteristics in patients with pulmonary hypertension

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目的 探讨三维心脏超声联合心电图(ECG)特征对肺动脉高压(PAH)患者心功能损害的诊断价值.方法选取2021年4月—2022年5月期间天津市安定医院收治的178例PAH患者,其中43例发生心功能损害,135例未发生心功能损害.比较2组三维心脏超声参数及ECG参数,并用受试者工作特征曲线(ROC)分析三维心脏超声参数及ECG参数对PAH发生心功能损害的诊断价值.结果 发生组右心室射血分数(RVEF)、三尖瓣环收缩期位移(TAPSE)值低于未发生组,右心室收缩压(RVSP)值则高于未发生组(P<0.05).2组的心率(HR)、校正后QT区间(QTc)、QRS电轴、V1导联R波幅、V1导联S波幅比较,差异无统计学意义(P>0.05),发生组QRS时限、V5导联S波幅大于未发生组,差异具有统计学意义(P<0.05).ROC曲线显示,三维心脏超声参数RVEF、RVSP、TAPSE单独诊断PAH发生心功能损害的曲线下面积(AUC)分别为0.686、0.701、0.735,三者联合诊断AUC为0.760;ECG参数QRS时限、V5导联S波幅单独诊断PAH发生心功能损害的AUC分别为0.730、0.701,二者联合诊断AUC为0.835;三维心脏超声和ECG联合诊断PAH患者心功能损害的灵敏度、特异度、AUC(0.95CI)分别为97.67%、69.63%、0.889(0.857~0.946),高于任一参数,两种方法联合诊断效能更高(P<0.05).结论 三维心脏超声和ECG均对PAH心功能损害有一定的诊断价值,两种方法联合诊断价值更高.
Objective To explore the diagnostic value of three-dimensional echocardiography combined with electro-cardiogram(ECG)in the cardiac function impairment of patients with pulmonary arterial hypertension(PAH).Methods 178 patients with PAH admitted to our hospital from April 2021 to May 2022 were selected,among which 43 had cardiac function impairment and 135 did not.The value of 3D echocardiographic parameters and ECG parameters in the diagnosis of cardiac function damage caused by PAH was analyzed by receiver operating characteristic curve(ROC).Re-sults The values of right ventricular ejection fraction(RVEF)and tricuspid ring systolic displacement(TAPSE)in the occurrence group were lower than those in the non-occurrence group,and the right ventricular systolic blood pressure(RVSP)was higher than those in the non-occurrence group(P<0.05).There were no statistically significant differ-ences in heart rate(HR),corrected QT interval(QTc),QRS electrical axis,V1 lead R amplitude and V1 lead S ampli-tude between the two groups(P>0.05),while QRS duration and V5 lead S amplitude in the occurrence group were higher than those in the non-occurrence group(P<0.05).ROC curve showed that the area under the curve(AUC)of RVEF,RVSP and TAPSE in the diagnosis of cardiac function impairment in PAH alone was 0.686,0.701 and 0.735,respectively,and the AUC of the combined diagnosis was 0.760.The AUC of ECG parameters QRS duration and V5 lead S amplitude for diagnosis of cardiac function impairment in PAH alone were 0.730 and 0.701,respectively,and the AUC of combined diagnosis was 0.835.The sensitivity,specificity and AUC(0.95CI)of 3D echocardiography and ECG in the diagnosis of cardiac function impairment in PAH patients were 97.67%,69.63%and 0.889(0.857~0.946),re-spectively,which were higher than any other parameter,and the combined diagnosis efficiency of the two methods was higher(P<O.05).Conclusion Both three-dimensional echocardiography and ECG are valuable in the diagnosis of car-diac function impairment in PAH,and the combined diagnosis of the two methods is more valuable.

Pulmonary hypertensionThree-dimensional cardiac ultrasoundElectrocardiogramCardiac function

高健、李基璨、谢立萍

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天津市安定医院功能科,天津 300222

肺动脉高压 三维心脏超声 心电图 心功能

2024

中国实验诊断学
吉林大学中日联谊医院 上海交通大学医学院附属瑞金医院

中国实验诊断学

CSTPCD
影响因子:1.273
ISSN:1007-4287
年,卷(期):2024.28(1)
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