The value of conventional MR combined with DWI imaging in differential diagnosis of primary cerebellar central nervous system lymphoma and advanced glioma
Objective to evaluate the value of conventional MRI morphological features combined with DWI imaging in distinguishing primary cerebellar central nervous system lymphoma((PCNSL))from high-grade glioma(HGG).Methods the imaging and clinical data of 16 patients with PCNSL and 28 patients with HGG confirmed by pathology were analyzed retrospectively.The differences of apparent diffusion coefficient((ADC))and conventional MRI parame-ters between PCNSL group and HGG group were compared by independent sample t-test or chi-square test.Results the ADC value of PCNSL group was lower than that of HGG group(0.53 X 10-3 vs.0.83 X 10-3 mm2/s,P＜0.001).There were significant differences in conventional MR features such as tumor size enhancement mode cystic edema and striated edema(all P＜0.05),but there was no significant difference in hemorrhage and brain surface involvement be-tween the two groups(all P＞0.0 5).Conclusion among the conventional MR features,tumor size,branching enhance-ment,cystic degeneration and stripe edema are helpful to distinguish cerebellar PCNSL from HGG,and the diagnostic ability can be further improved when combined with ADC value.
primary central nervous system lymphomagliomamagnetic resonancediagnosis
NETL
NSTL
万方数据
