Objective To explore the relationship between fetal aortopulmonary Doppler parameters and neonatal respiratory distress syndrome(NRDS)and their predictive value.Methods A total of 136 cases were included in the study in which fetal aortopulmonary Doppler parameters were obtained prior to delivery.According to neonatal out-comes,59 patients were divided into NRDS group and 77 cases in non-NRDS group.Comparing the Doppler parameters of the two groups of fetal aortopulmonary artery,the Receiver operator characteristic curve(ROC)analysis was plotted and the area under the curve(AUC)was calculated,the maximum cut-off value was obtained according to the maximum Youden's index,and the sensitivity,specificity and accuracy of the AT/ET ratio in predicting NRDS were calculated.Results The PSV,AT,AT/ET ratio parameters of fetal aortopulmonary Doppler ultrasound in the NRDS group were significantly lower than those in the control group,and the difference was statistically significant(P＜0.05).The fetal aortopulmonary AT/ET ratio had an AUC of 0.957 in predicting neonatal NRDS,and the maximum cut-off value was 0.833 based on the maximum Youden's index.The sensitivity,specificity and accuracy were 93.5％,89.8％and 92.7％,respectively.Conclusion The measurement of AT/ET ratio by prenatal aortopulmonary artery Doppler has significant value in the prediction of neonatal respiratory distress syndrome.
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