胎儿肺动脉多普勒参数对预测新生儿呼吸窘迫综合征的价值
The value of fetal pulmonary Doppler parameters in predicting neonatal respiratory distress syndrome
崔明雨 1南钰 1刘宗谕 1崔雪 1卢怡璇 1范丽梅1
作者信息
- 1. 吉林大学白求恩第二医院妇产科,吉林长春 130012
- 折叠
摘要
目的 探讨胎儿主肺动脉多普勒参数与新生儿呼吸窘迫综合征(NRDS)的关系及预测价值.方法 研究共纳入136例病例,临产前获取胎儿主肺动脉多普勒参数.根据新生儿结局分为NRDS组59例及非NRDS组77例.比较两组胎儿主肺动脉多普勒参数,绘制受试者工作特征曲线(ROC)并计算曲线下面积(AUC),根据最大约登指数获得最大临界值,并计算AT/ET比值在预测NRDS的敏感度、特异度、准确度.结果 NRDS组胎儿主肺动脉PSV、AT、AT/ET比值均明显低于对照组,差异具有统计学意义(P＜0.05).胎儿主肺动脉AT/ET比值在预测新生儿NRDS上的AUC为0.957,根据最大约登指数获得最大临界值为0.833,敏感度、特异度、准确度分别为93.5％、89.8％、92.7％.结论 胎儿主肺动脉AT/ET比值对新生儿NEDS的预测有显著价值.
Abstract
Objective To explore the relationship between fetal aortopulmonary Doppler parameters and neonatal respiratory distress syndrome(NRDS)and their predictive value.Methods A total of 136 cases were included in the study in which fetal aortopulmonary Doppler parameters were obtained prior to delivery.According to neonatal out-comes,59 patients were divided into NRDS group and 77 cases in non-NRDS group.Comparing the Doppler parameters of the two groups of fetal aortopulmonary artery,the Receiver operator characteristic curve(ROC)analysis was plotted and the area under the curve(AUC)was calculated,the maximum cut-off value was obtained according to the maximum Youden's index,and the sensitivity,specificity and accuracy of the AT/ET ratio in predicting NRDS were calculated.Results The PSV,AT,AT/ET ratio parameters of fetal aortopulmonary Doppler ultrasound in the NRDS group were significantly lower than those in the control group,and the difference was statistically significant(P＜0.05).The fetal aortopulmonary AT/ET ratio had an AUC of 0.957 in predicting neonatal NRDS,and the maximum cut-off value was 0.833 based on the maximum Youden's index.The sensitivity,specificity and accuracy were 93.5％,89.8％and 92.7％,respectively.Conclusion The measurement of AT/ET ratio by prenatal aortopulmonary artery Doppler has significant value in the prediction of neonatal respiratory distress syndrome.
关键词
主肺动脉/超声多普勒/AT/ET比值/新生儿呼吸窘迫综合征Key words
Aortopulmonary artery/Ultrasound Doppler/AT/ET ratio/Neonatal respiratory distress syndrome引用本文复制引用
基金项目
吉林省卫生健康科技能力提升项目(2021LC017)
出版年
2024
NETL
NSTL
万方数据