Clinical relationship between chronic obstructive pulmonary disease and pathological types of lung cancer and suggestive im-plications for patient prognosis
Objective to explore the clinical characteristics of different pathological types of lung cancer complicated with chronic obstructive pulmonary disease(COPD),and to explore its significance for prognosis.Methods the clinical data of 200 patients with chronic airway inflammatory diseases from January 2021 to August 2023 were retrospectively analyzed.According to the presence or absence of lung cancer,the patients were divided into two groups:COPD with lung cancer group and COPD group.The pathological features,incidence,treatment and prognosis of the two groups were compared and analyzed.Results All patients in both groups were followed up successfully.There were significant differences in chest pain,dyspnea,pleural effusion,FVE1/FVC and ADC value of necrotic area between lung cancer group and lung cancer complicated with COPD group(P＜0.05).The survival rate,PFSE and OS of lung cancer group were significantly higher than those of lung cancer combined with COPD group(P＜0.05).Logstic regression analysis showed that pleural effusion,FVE1/FVC,chest pain,smoking history and high ADC value in necrotic area were all risk factors for lung cancer complicated with COPD(P＜0.05).There were statistical differences between the treatment of the three groups and the prognosis of mortality,recurrence and metastasis rate of early lung cancer and cancer control rate during the one-year follow-up period(P＜0.05).Conclusion chronic obstructive pulmonary disease is closely relat-ed to the pathological type of lung cancer.Different pathological types of lung cancer and chronic obstructive pulmonary disease have different early clinical symptoms and signs.Combined treatment of COPD and lung cancer is helpful to im-prove the prognosis of chronic obstructive pulmonary disease complicated with lung cancer.
Chronic obstructive pulmonary diseaseLung cancer pathological typePrognosis
NETL
NSTL
万方数据
