肺炎支原体与流感病毒混合感染患儿WBC、CRP指标变化监测
Monitoring the changes of WBC and CRP in children with mixed infection of mycoplasma pneumoniae and influenza virus
李莉 1刘建华 2王杨 1邢桂荣 1王天成1
作者信息
- 1. 首都医科大学附属北京世纪坛医院新生儿科,北京 100038
- 2. 北京儿童医院顺义妇儿医院儿科,北京 101300
- 折叠
摘要
目的 分析白细胞计数(White blood cell count,WBC)、C反应蛋白(C-reactive protein,CRP)在肺炎支原体与流感病毒混合感染患儿中的表达及意义.方法 选取2020年2月到2022年2月北京世纪坛医院和北京儿童医院顺义妇儿医院收治的164例肺炎支原体与流感病毒混合感染患儿为混合感染组,选取单纯肺炎支原体感染患儿95例为支原体感染组,另选取健康体检志愿者69例为对照组.检测三组WBC、CRP水平.结果 与对照组相比,支原体感染组、混合感染组WBC、CRP水平较高(P＜0.05);与支原体感染组相比,混合感染组WBC、CRP水平较高(P＜0.05).与预后良好患儿相比,预后不良患儿WBC、CRP水平较高(P＜0.05).ROC曲线显示,两项联合对肺炎支原体与流感病毒混合感染的诊断价值高于WBC、CRP单项检测(P＜0.05).结论 肺炎支原体与流感病毒混合感染患儿WBC、CRP水平较高,且随入院时间的延长WBC、CRP水平升高加剧,入院第3d WBC、CRP水平最高,联合检测对流感病毒混合感染患儿的诊断价值较高.
Abstract
Objective The expression and significance of white blood cell count(White blood cell count,WBC)and C-reactive protein(C-reactive protein,CRP)were analyzed in children with mixed infection of Mycoplasma pneumoniae and influenza virus.Methods A total of 164 children with mycoplasma pneumoniae and influenza virus treated in our hospital from February 2020 to February 2022 were selected as the mixed infection group,95 children with mycoplasma pneumoniae infection were selected as the mycoplasma infection group,and 69 healthy examination volunteers were se-lected as the control group.The levels of WBC and CRP were detected in the three groups.Results Compared with the control group,WBC and CRP were higher in the mycoplasma infected and mixed-infected group(P＜0.05),and WBC and CRP in the mixed infection group compared with the mycoplasma infected group(P＜0.05).Compared with chil-dren with good prognosis,WBC and CRP levels were higher in children with poor prognosis(P＜0.05).The ROC curve showed that the diagnostic value of the two combined tests for mixed M.pneumoniae and influenza virus infection was higher than that of the WBC and CRP single tests(P＜0.05).Conclusion Children with mixed mycoplasma pneumoni-ae infection with influenza virus had high levels of WBC and CRP,and the levels of WBC and CRP increased with the extension of admission time.The levels of WBC and CRP were the highest on admission,and the combined test had high diagnostic value for children with mixed influenza virus infection.
关键词
肺炎支原体/流感病毒/白细胞计数/C反应蛋白Key words
Mycoplasma pneumoniae/Influenza virus/White blood cell count/C-reactive protein引用本文复制引用
出版年
2024
NETL
NSTL
万方数据