Objective To explore the correlation between intraoperative hypotension defined as mean arterial pres-sure less than 60 mmHg and postoperative delirium,to provide clinical reference.Methods This study was a retrospec-tive cohort study.A total of 508 patients who underwent thoracic surgery in West China Hospital of Sichuan University from December 2020 to November 2021 were included.The data of patients included:general condition,preoperative sleep score,preoperative cognitive function,surgery-related data,cluster intervention strategy,postoperative destina-tion,postoperative delirium,intraoperative blood pressure data,etc.Binary Logistic regression,multiple Logistic regres-sion and subgroup analysis were used for statistical analysis.Results This study found that intraoperative hypotension did not directly affect the incidence of postoperative delirium.Subgroup analysis showed that postoperative delirium pa-tients with intraoperative hypotension were more likely to present with depressive delirium.Smokers and patients with-out cluster intervention strategies are more likely to have postoperative delirium after intraoperative hypotension.Ad-vanced age,poor preoperative sleep and thoracotomy are independent risk factors for postoperative delirium.Conclusion There is no direct correlation between intraoperative hypotension and postoperative delirium,but the effect of intrao-perative hypotension may be amplified when the patient has other risk factors for delirium.For patients with mean arte-rial pressure＜60 mmHg at least once during operation,more attention should be paid to the cognitive function of pa-tients after operation,and the depressive delirium without obvious clinical manifestations should be identified in time.
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