Objective To investigate the factors associated with the occurrence of visual disability in elderly patients with diabetic retinopathy(DR).Methods Patients with diabetic retinopathy who attended the clinic from May 2020 to December 2023 were enrolled,and the first 198 patients were included in the modelling group and the rest 184 patients were included in the validation group according to the chronological order of the clinic visit.Results The prevalence of visual disability among DR patients in the modelling group was 43.0％.Visual disability was associated with gender,fasting glucose,duration of diabetes mellitus,co-morbidities,urinary protein and intraocular pressure(P＜0.05).Multi-factorial logistic regression indicated that the above factors were independent risk factors for the development of visual disability.Hosmer-Lemeshow goodness-of-fit test showed a better model fit in the modelling group versus the valida-tion group(x2=9.33,P=0.31;x2=11.21,P=0.19).The area under the ROC curve was 0.919 in the modelling group,with a maximal Yoden index of 0.674,sensitivity 0.782,and specificity 0.892;the validation group was 0.841,maximum Jordon's index 0.564,sensitivity 0.827,and specificity 0.737.Conclusion The model established in this study can effectively predict the occurrence of visual disability in patients with diabetic retinopathy,and provide value for early clinical diagnosis and intervention.
维普
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