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兽用抗菌复方制剂研究进展

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随着动物感染性疾病的复杂化和细菌耐药性的发展,兽医临床急需对混合感染和耐药菌有效的新型抗菌药物,但新药开发难度大、费用高、周期长。抗菌药联合使用既可以增加抗菌谱,又可以防止耐药性出现,在疾病治疗中起着重要的作用。复方制剂是抗菌药联合使用的简易形式,因此兽用复方制剂研制具有广阔发展空间。本文总结了兽用抗菌复方制剂研发、批准和使用情况的研究进展,提出了兽用抗菌复方制剂研发中存在的主要问题,为今后相关的科学研究和产品研发提供了一定的参考。
Research Progress on Veterinary Antimicrobial Compound Preparations
With the increasing complexity of animal infectious diseases and the development of bacterial resistance,there is a pressing need for novel antibacterial drugs that are effective against mixed infections and resistant bacteria in veterinary clinical practice.However,the development of new drugs is challenging,expensive,and time-consuming.The combined use of antimicrobial drugs can broaden the antimicrobial spectrum and prevent resistance,playing a crucial role in disease treatment.Compound preparations,as a simplified form of combined antimicrobial drug usage,offer vast potential for development in veterinary medicine.This paper summarizes the research progress in the development,approval,and use of veterinary antibacterial compound preparations,highlighting the main issues in their development.The findings provide a reference for future scientific research and product development in this field.

veterinary medicinecompound preparationantibioticdrug combination

王茹、寇紫艳、田校源、黄玲利

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华中农业大学动物医学院 国家兽药残留基准实验室,湖北 武汉 430070

国家兽药安全评价实验室,湖北 武汉 430070

农业农村部兽药残留检测重点实验室,湖北 武汉 430070

兽药 复方制剂 抗菌药 联合用药

2025

中国兽医杂志
中国畜牧兽医学会

中国兽医杂志

北大核心
影响因子:0.343
ISSN:0529-6005
年,卷(期):2025.61(1)