首页|短时程脊髓电刺激预防老年带状疱疹后神经痛的临床研究

短时程脊髓电刺激预防老年带状疱疹后神经痛的临床研究

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目的:探究短时程脊髓电刺激(short-term spinal cord stimulation,st-SCS)治疗老年带状疱疹神经痛及预防带状疱疹后神经痛(postherpetic neuralgia,PHN)的疗效.方法:选取2020年8月至2022年11月于中日友好医院疼痛科就诊的带状疱疹病人200例.采用随机数字表法分为药物治疗组(M组)和短时程脊髓电刺激治疗组(S组).M组给予常规药物治疗,S组给予st-SCS治疗,观察两组病人治疗前、治疗后2周、1个月和3个月的疼痛、睡眠、生活质量变化,以及并发症与疾病转归情况.结果:最终共纳入 168 例,其中M组 90 例,S组 78 例.两组病人的疼痛视觉模拟评分法(visual analogue scale,VAS)评分、阿森斯睡眠量表(Athens insomnia scale,AIS)及生活质量QL-index量表评分均较治疗前改善(P<0.001),且S组改善更加明显(P<0.05).治疗3个月后,S组PHN的发生率低于M组(P<0.05).结论:st-SCS可以改善老年带状疱疹神经痛且对PHN的发生具有一定的预防作用.
A clinical study on prevention of postherpetic neuralgia in the elderly by short-term spinal cord stimulation
Objective:To explore the efficacy of short-term spinal cord stimulation in the treatment of elderly herpes zoster pain and the prevention of postherpetic neuralgia.Methods:Two hundred herpes zoster patients who visited the Pain Department of China-Japanese Friendship Hospital from August 2020 to November 2022 were selected.The patients were divided into a medication treatment group(M group)and a short-term spinal cord stimulation treatment group(S group)by the random number table.M group was given routine medication treatment,while S group received short-term spinal cord stimulation treatment.The pain,sleep,quality of life,complications,and prognosis of disease in two groups were observed.Results:A total of 168 patients were ultimately enrolled,including 90 in M group and 78 in S group.The visual analogue scale(VAS)score,Athens insomnia scale(AIS)score,and QL-index scale in both groups improved compared with before treat-ment(P<0.001),while the improvement in group S was more significant(P<0.05).After 3 months of treatment,the incidence of PHN in S group was lower than that in S group(P<0.05).Conclusion:Short-term spinal cord stim-ulation can improve elderly herpes zoster neuralgia and has a preventive effect on the occurrence of PHN.

short-term spinal cord stimulationherpes zosterpostherpetic neuralgiaprevention

胡慧敏、王晓越、张媛婧、张毅、李怡帆、毛鹏、樊碧发

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北京中医药大学研究生院,北京 100029

中日友好医院疼痛科,北京 100029

短时程脊髓电刺激 带状疱疹 带状疱疹后神经痛 预防

首都卫生发展科研专项

首发2022-1-4061

2024

中国疼痛医学杂志
北京大学,中华医学会疼痛学分会

中国疼痛医学杂志

CSTPCD北大核心
影响因子:1.457
ISSN:1006-9852
年,卷(期):2024.30(1)
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