Progress in studying the regulatory role and mechanism of vitamin D in chronic pain
Chronic pain,affecting over 30%of the global population,has emerged as a significant public health concern.Due to the complex pathophysiological mechanisms involved in its generation and maintenance,the effect of current clinical treatment is unsatisfactory,leading to considerable distress to patients.Vitamin D,is an essential fat soluble vitamin for the human body,and is now also considered a multifunctional neurosteroid.Research has shown that vitamin D can effectively alleviate chronic pain,but the regulatory mechanism of vitamin D on chronic pain is not yet fully understood.This article will provide a review on the regulation of chronic pain by vitamin D and its related mechanisms,offering novel therapeutic insights for pain.