The pathogenesis of persistent somatoform pain disorder
Persistent somatoform pain disorder(PSPD)is a common and complex clinical disease and a subtype of the somatoform disorder.Patients usually have repeated visits,uncertain treatment outcomes,and high level of anxiety.The pathogenesis of PSPD is currently unclear,and there are no specific drugs available.Clinical treatment is mostly based on antidepressant drugs,antipsychotic drugs and other drug treatment,combined with psychotherapy.In this paper,we review and summarize the recent research progress of PSPD in neurophysiological mechanisms,in order to provide reference for clarifying the pathogenesis of PSPD.