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持续性躯体形式疼痛障碍的发病机制

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持续性躯体形式疼痛障碍(persistent somatoform pain disorder,PSPD)是临床较常见且复杂的疾病,是"躯体形式障碍"的一个亚型,病人通常反复就诊、疗效不确定且伴高度焦虑.PSPD的发病机制目前尚不明确,暂无特效药物,临床治疗多以抗抑郁药、抗精神病药等药物治疗为主,并联合心理疗法.本文回顾总结近年来PSPD在神经生理机制方面的研究进展,以期为明确PSPD的发病机制提供参考.
The pathogenesis of persistent somatoform pain disorder
Persistent somatoform pain disorder(PSPD)is a common and complex clinical disease and a subtype of the somatoform disorder.Patients usually have repeated visits,uncertain treatment outcomes,and high level of anxiety.The pathogenesis of PSPD is currently unclear,and there are no specific drugs available.Clinical treatment is mostly based on antidepressant drugs,antipsychotic drugs and other drug treatment,combined with psychotherapy.In this paper,we review and summarize the recent research progress of PSPD in neurophysiological mechanisms,in order to provide reference for clarifying the pathogenesis of PSPD.

persistent somatoform pain disorderpainpathogenesis

李卓伦、孙武平、熊东林

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华中科技大学协和深圳医院疼痛科,深圳市疼痛学实验室,深圳 518052

持续性躯体形式疼痛障碍 疼痛 机制

深圳市卫南山区技术研发和创意设计项目

NS2021014

2024

中国疼痛医学杂志
北京大学,中华医学会疼痛学分会

中国疼痛医学杂志

CSTPCD北大核心
影响因子:1.457
ISSN:1006-9852
年,卷(期):2024.30(3)
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