持续性躯体形式疼痛障碍的发病机制
The pathogenesis of persistent somatoform pain disorder
李卓伦 1孙武平 1熊东林1
作者信息
- 1. 华中科技大学协和深圳医院疼痛科,深圳市疼痛学实验室,深圳 518052
- 折叠
摘要
持续性躯体形式疼痛障碍(persistent somatoform pain disorder,PSPD)是临床较常见且复杂的疾病,是"躯体形式障碍"的一个亚型,病人通常反复就诊、疗效不确定且伴高度焦虑.PSPD的发病机制目前尚不明确,暂无特效药物,临床治疗多以抗抑郁药、抗精神病药等药物治疗为主,并联合心理疗法.本文回顾总结近年来PSPD在神经生理机制方面的研究进展,以期为明确PSPD的发病机制提供参考.
Abstract
Persistent somatoform pain disorder(PSPD)is a common and complex clinical disease and a subtype of the somatoform disorder.Patients usually have repeated visits,uncertain treatment outcomes,and high level of anxiety.The pathogenesis of PSPD is currently unclear,and there are no specific drugs available.Clinical treatment is mostly based on antidepressant drugs,antipsychotic drugs and other drug treatment,combined with psychotherapy.In this paper,we review and summarize the recent research progress of PSPD in neurophysiological mechanisms,in order to provide reference for clarifying the pathogenesis of PSPD.
关键词
持续性躯体形式疼痛障碍/疼痛/机制Key words
persistent somatoform pain disorder/pain/pathogenesis引用本文复制引用
基金项目
深圳市卫南山区技术研发和创意设计项目(NS2021014)
出版年
2024
NETL
NSTL
万方数据