首页|经皮微球囊压迫术和射频热凝术治疗原发性三叉神经痛的有效性和安全性研究

经皮微球囊压迫术和射频热凝术治疗原发性三叉神经痛的有效性和安全性研究

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目的:比较经皮微球囊压迫术和射频热凝术治疗原发性三叉神经痛(primary trigeminal neural-gia,PTN)的疗效及安全性.方法:回顾性分析2020年11月至2022年3月中日友好医院疼痛科收治的PTN病人,根据手术方式不同分为经皮球囊压迫组(P组)55例和射频热凝组(R组)53例.观察两组术前、术后1小时的视觉模拟评分法(visual analogue scale,VAS)评分、总体疗效、并发症发生情况,随访两组术后1个月、3个月、6个月、1年的疼痛复发率.结果:两组病人术前VAS评分差异无统计学意义,术后1小时VAS评分明显低于术前(P<0.01),两组术后1小时的VAS评分比较差异无统计学意义.两组总有效率比较差异无统计学意义.经皮球囊压迫组的整体面部麻木程度较射频热凝组轻(P<0.05),两组术后出现口唇疱疹、角膜反射下降、干眼症、咀嚼肌无力的差异无统计学意义.两组病人术后1个月、3个月、6个月、1年复发率比较差异无统计学意义,1年后射频热凝组的复发率更高.结论:经皮微球囊压迫术和射频热凝术均可有效治疗PTN,均可出现面部麻木等并发症,1年后射频热凝组的复发率更高.
The efficacy and safety of percutaneous balloon compression and radiofrequency thermocoagulation in the treatment of primary trigeminal neuralgia
Objective:To compare the efficacy and safety of percutaneous balloon compression with radiofrequency thermocoagulation in the treatment of primary trigeminal neuralgia(PTN).Methods:PTN patients admitted to the Pain Department of China-Japan Friendship Hospital from November 2020 to March 2022 were retrospectively analyzed and divided into percutaneous balloon compression(PBC)group(group P,n = 55)and radiofrequency thermocoagulation(RFT)group(group R,n = 53)according to different operation methods.Visual analogue scale(VAS),total efficacy and complications of the two groups were observed before and 1 hour after surgery.Pain recurrence rates of the two groups were followed up 1 month,3 months,6 months and 1 year after surgery.Results:There was no statistical difference in preoperative VAS score between the two groups,and the VAS score 1 hour after surgery was significantly lower than the preoperative basic value(P<0.01),and there was no statistical difference in the VAS score 1 hour after surgery between the two groups.There was no significant difference in total effective rate between the two groups.The overall degree of facial numbness in group P was less severe than that in group R(P<0.05),and there was no significant difference in herpes labialis,decreased corneal reflex,xerophthalmia and masticatory muscle asthenia between the two groups.There was no significant difference in recurrence rate at 1 month,3 months,6 months and 1 year between the two groups.The recurrence rate was higher in group R after 1 year.Conclusion:Percutaneous balloon compression and radiofrequency thermocoagulation are both effective in the treatment of PTN,and both can cause complications such as facial numbness,and the recurrence rate is higher in the RFT after 1 year.

primary trigeminal neuralgia(PTN)percutaneous balloon compressionradiofrequency thermoco-agulationcurative effectcomplication

张媛婧、王稳、刘春华、努尔比亚·阿布拉、李怡帆、樊碧发

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北京中医药大学研究生院,北京 100029

中日友好医院疼痛科,北京 100029

原发性三叉神经痛 经皮球囊压迫术 射频热凝术 疗效 并发症

国家重点研发计划

2022YFC3602201

2024

中国疼痛医学杂志
北京大学,中华医学会疼痛学分会

中国疼痛医学杂志

CSTPCD北大核心
影响因子:1.457
ISSN:1006-9852
年,卷(期):2024.30(3)
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