Research progress on the mechanism of acupuncture relieving knee osteoarthritis associated pain
Knee osteoarthritis(KOA)is a common degenerative disease,extremely prevalent among older population,and is often associated with pain,movement disorders,and reduced quality of life.Although drugs can relieve the painful symptoms of KOA,long-term use inevitably produces adverse reactions.Acupuncture is an effective non-drug treatment that relives KOA pain and improves patients'quality of life.In the world,there are few reviews on the mechanism of acupuncture in the treatment of KOA pain.This paper profits from the pain conduction pathway and focuses on the analgesic mechanism of acupuncture,including the action of acupuncture on peripheral tissues and organs and the central nervous system to relieve joint pain and improve joint function,through regulating the nociceptive conduction and immune inflammatory factors,as well as promoting the release of endogenous analgesic substances.The origin of KOA pain and the mechanism of acupuncture to relieve KOA pain are briefly discussed in order to provide theoretical basis and therapeutic ideas for promoting the clinical practice of acupuncture treatment of KOA pain.
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