Peripheral and central mechanisms of electroacupuncture in alleviating chronic inflammatory pain
Pain is a distressing experience associated with actual or potential tissue damage with sensory,emotional,cognitive and social components.In particular,inflammatory pain has a high clinical incidence,and current therapeutic drugs have certain adverse reactions.Therefore,there is an urgent need for novel,safe and effective treatment methods.Electroacupuncture has emerged as a promising intervention due to its practicality,ease of operation,and minimal adverse effects.Despite its widespread use in clinical and basic research,the precise mechanisms underlying electroacupuncture's efficacy in relieving chronic inflammatory pain remain unclear.This review aims to summarize recent advances in the understanding of peripheral and central mechanisms related to electroacupuncture-induced analgesia for chronic inflammatory pain.It seeks to provide a theoretical foundation and scientific references to guide clinical applications of electroacupuncture.