Treatment of postherpetic neuralgia by injecting autologous plasma activated with ozone into the intervertebral foramen and superficial fascia
Objective:We aim to investigate the effectiveness and safety of injection of autologous plasma activated with ozone into the intervertebral foramen and superficial fascia for the treatment of postherpetic neuralgia(PHN).Methods:From May 4,2023 to July 14,2023,a total of 30 patients with PHN were selected from the Pain Department of Dongfang Hospital Beijing University of Chinese Medicine.All patients received treatment with the injection of autologous plasma activated with ozone into their respective intervertebral foramen and superficial fascia on the injuried side.The treatment efficacy and adverse reactions of all patients will be recorded,and the Numerical rating scale(NRS),Self-rating anxiety scale(SAS),Self-rating depression scale(SDS),Pittsburg sleep quality index(PSQI),and quality of life(QOL)scores will be compared before and 1 week,2 weeks,and 1 month after treatment.Results:The overall effective rate of treatment for all patients amounts to 93.3%,with no significant adverse reactions or events occurring.Following treatment for 1 week,2 weeks,and 1 month,the overall scores of NRS,SAS,SDS,and PSQI for all patients were significantly reduced compared to those before treatment,with statistically significant differences(P<0.001).The overall score of QOL was significantly higher than before treatment,indicating statistically significant differences(P<0.001).The overall difference among different time points is statistically significant(P<0.001).Conclusion:The treatment of postherpetic neuralgia through injection of autologous plasma activated with ozone into the intervertebral foramen and superficial fascia is not only highly effective but also no significant adverse reactions or events.It can greatly reduce the pain level of patients suffering from postherpetic neuralgia,thereby enhancing their emotional state,sleep,and quality of life,while also boasting high safety.
postherpetic neuralgiaozoneautologous plasmaintervertebral foramensuperficial fascia
万方数据
维普
