Progress of clinical and mechanistic studies on acupuncture in the treatment of cancer induced bone pain
Cancer induced bone pain(CIBP)is the most common kind of moderate and severe cancer pain,and its pathogenesis is complicated.Mechanistic studies have focused on spinal neuron activation,glial cell activation,activation of different receptors and so on.Modern medicine have some toxic side events.Clinical studies have shown that acupuncture can reduce drug tolerance and side effects,reduce the dosage of analgesics,improve anxiety and depression,and thus improve the patients'quality of life.Its mechanisms include regulating the release of neurotransmitters,inhibiting glial cell activation and regulating descending inhibition and facilitation system.This paper reviewed the researches on the pathogenesis of CIBP,as well as the clinical and basic studies on the acupuncture treatment for CIBP,hoping to provide further evidence on the clinical application and mechanism researches on acupuncture in relieving pain.
cancer induced bone painacupunctureanalgesiaresearch progress
万方数据
维普
