不同模式经颅磁刺激治疗神经病理性疼痛的研究进展
Application of different modes of transcranial magnetic stimulation for neuropathic pain
吴思杏 1纪运 1马柯1
作者信息
- 1. 上海交通大学医学院附属新华医院疼痛科,上海 200092
- 折叠
摘要
神经病理性疼痛是由于躯体感觉系统的损害或疾病引起的疼痛,其发生机制可能与伤害性感受器敏化、传入神经元异常的异位兴奋性、脊髓后角促伤害感受的易化等有关.经颅磁刺激是一种无创、非侵入性的治疗神经病理性疼痛的手段,可以有效缓解疼痛.本文就经颅磁刺激治疗神经病理性疼痛的可能机制、不同模式的临床应用、安全性等方面进行综述,旨在为进一步研究经颅磁刺激治疗神经病理性疼痛提供参考及理论依据.
Abstract
Neuropathic pain is caused by a lesion or disease to the somatosensory nervous system,and its mechanism may be related to sensitization of injury receptors,abnormal ectopic excitability of afferent neurons,and vulnerability of the posterior horn of the spinal cord to injury perception.Transcranial magnetic stimulation is a noninvasive treatment for neuropathic pain and can effectively relieve pain.This article reviews and introduces the possible mechanisms,clinical application of different modalities,and safety of transcranial magnetic stimulation for the treatment of neuropathic pain,aiming to provide reference and theoretical basis for further research on the treatment of neuropathic pain with transcranial magnetic stimulation.
关键词
经颅磁刺激/神经病理性疼痛/重复经颅磁刺激/θ节律爆发式磁刺激Key words
transcranial magnetic stimulation/neuropathic pain/repetitive transcranial magnetic stimulation/theta rhythm burst magnetic stimulation引用本文复制引用
基金项目
国家自然科学基金面上项目(82371224)
上海交通大学"交大之星"重点项目(20230103)
出版年
2024
NETL
NSTL
万方数据