首页|短时程脊髓电刺激与双极脉冲射频治疗带状疱疹后神经痛的临床研究

短时程脊髓电刺激与双极脉冲射频治疗带状疱疹后神经痛的临床研究

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目的:比较短时程脊髓电刺激(short-term spinal cord stimulation,stSCS)和双极脉冲射频(bipolar pulse radiofrequency,bPRF)治疗带状疱疹后神经痛(postherpetic neuralgia,PHN)的临床疗效.方法:选取2021年9月至2022年12月福建医科大学附属第一医院收治的108例PHN病人为研究对象,按手术方式分为stSCS组(40例)和bPRF组(68例).采用视觉模拟评分法(visual analogue scale,VAS)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS)等指标评估临床疗效.结果:两组病人术后各时间点VAS、PSQI、SAS和SDS评分均较术前(T0)显著降低(P<0.05).术后 6 个月(T7)、9 个月(T8)、12个月(T9)时stSCS组VAS评分显著低于bPRF组(P<0.05),术后 1天(T1)、7天(T2)、14 天(T3)、28天(T4)、2个月(T5)、3个月(T6)两组VAS评分无显著差异;T8和T9时stSCS组病人PSQI、SAS和SDS评分显著低于bPRF组(P<0.05),但T1至T7时,这些评分两组之间差异无统计学意义.结论:stSCS组和bPRF组在近期疗效上相当,均可安全有效地治疗PHN.在远期疗效上stSCS组显示出更明显的优势.
Clinical study of short-term spinal cord electrical stimulation and bipolar pulse radiofrequency therapy for postherpetic neuralgia
Objective:To compare the clinical efficacy of short-term spinal cord stimulation(stSCS)and bipolar pulse radiofrequency(bPRF)in the treatment of postherpetic neuralgia(PHN).Methods:A total of 108 patients with PHN admitted to the First Affiliated Hospital of Fujian Medical University from September 2021 to December 2022 were selected as the study objects,and they were divided into stSCS group(40 cases)and bPRF group(68 cases)according to operation methods.Visual analogue scale(VAS),Pittsburgh sleep quality index(PSQI),self-rating anxiety scale(SAS),and self-rating depression scale(SDS)were used to evaluate clinical efficacy.Results:The scores of VAS,PSQI,SAS,and SDS in both groups were significantly lower than those before surgery(T0)at all time points(P<0.05).The VAS score of stSCS group was significantly lower than that of bPRF group at 6 months(T7),9 months(T8),and 12 months(T9)(P<0.05)while there was no significant difference on 1 day(T1),7 days(T2),14 days(T3),28 days(T4),2 months(T5),and 3 months(T6)after surgery.The PSQI,SAS,and SDS scores in stSCS group were significantly lower than those in bPRF group at T8 and T9(P<0.05)but there was no significant difference at T1 to T7.Conclusion:The short-term efficacy of stSCS group and bPRF group is similar,and both can safely and effectively treat PHN.The long-term therapeutic advantage of the stSCS group is more significant.

postherpetic neuralgiashort-term spinal cord stimulationbipolar pulse radiofrequencyclinical efficacy

陈嘉芳、何龙、林鹏、莫海兵、谢恬、庄国雄、林章雅、江昊

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福建医科大学附属第一医院 疼痛科,福州 350000

福建医科大学附属第一医院滨海院区国家区域医疗中心,福州 350212

福建医科大学神经外科研究所,福州 350005

福建医科大学附属第一医院闽南医院麻醉科,泉州 362801

福建医科大学附属第一医院 神经外科,福州 350000

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带状疱疹后神经痛 短时程脊髓电刺激 双极脉冲射频 临床疗效

福建省卫生健康中青年骨干人才培养项目2023年福建省财政厅专项经费福建医科大学启航基金

2023GGA032BPB-2023LZY-22020QH1046

2024

中国疼痛医学杂志
北京大学,中华医学会疼痛学分会

中国疼痛医学杂志

CSTPCD北大核心
影响因子:1.457
ISSN:1006-9852
年,卷(期):2024.30(9)