首页|经椎间孔硬膜外联合双侧L2神经根阻滞治疗盘源性腰痛的临床研究

经椎间孔硬膜外联合双侧L2神经根阻滞治疗盘源性腰痛的临床研究

扫码查看
目的:评价经椎间孔硬膜外联合双侧L2 神经根阻滞治疗盘源性腰痛(discogenic low back pain,DLBP)的临床疗效.方法:采用前瞻性随机对照研究方法,选取2022年6月至2023年6月中日友好医院疼痛科符合纳入标准的慢性盘源性腰痛病人,计算机产生随机数字表法分为研究组和对照组,研究组采用病变间盘节段硬膜外阻滞联合L2 神经根阻滞,对照组采用病变间盘节段硬膜外阻滞.评价两组治疗后第1、3、6个月疼痛数字分级评分法(numerical rating scale,NRS)评分、Oswestry功能障碍指数(Oswestry disability index,ODI)评分.结果:符合纳入标准的DLBP病人共92例,研究组(n=46)和对照组(n=46).治疗后第1、3个月研究组和对照组NRS评分分别为1.7±0.6 vs.2.7±0.4和2.2±0.4 vs.3.2±0.5,两组比较差异有统计学意义(P<0.05).治疗后第1、3个月研究组和对照组ODI评分分别为12.2±1.7 vs.17.4±2.1和16.1±2.1 vs.20.4±2.9,两组比较差异有统计学意义(P<0.05).治疗后第6个月研究组和对照组NRS评分分别为3.0±0.5 vs.3.2±0.6,ODI评分分别为21.4±2.0 vs.23.1±1.7,两组NRS、ODI评分差异均无统计学意义.与基础值相比,两组在治疗后第 1、3、6个月NRS、ODI评分均显著降低(P<0.001).结论:经椎间孔硬膜外阻滞能够有效减轻DLBP,改善运动障碍.联合L2神经根通路治疗较单纯硬膜外阻滞更有效.
Clinical study of transforaminal epidural combined bilateral L2 nerve root block in the treatment of discogenic low back pain
Objective:To evaluate the clinical efficacy of transforaminal epidural combined bilateral L2 nerve root block in the treatment of discogenic low back pain.Methods:A prospective randomized controlled method was conducted.From June 2022 to June 2023,patients with chronic discogenic low back pain who met the inclusion criteria were screened in the Pain Department of China-Japan Friendship Hospital.The patients in study group underwent transforaminal epidural block at affected intervertebral discs level and bilateral L2 nerve root block,while the patients in control group only experienced transforaminal epidural block.Numerical rating scale(NRS)pain score and Oswestry disability index(ODI)score were recorded at time before procedure and the 1st,the 3rd,and the 6th month after treatment.Results:A total of 92 DLBP patients who met the inclusion criteria were divided into study group(n=46)and control group(n=46).At the 1st and the 3rd month after treatment,the NRS scores of the study group and the control group were 1.7±0.6 vs.2.7±0.4 and 2.2±0.4 vs.3.2±0.5,respectively,with statistically significant differences between the two groups(P<0.05).At the 1st and the 3rd month after treatment,the ODI scores of the study group and the control group were 12.2±1.7 vs.17.4±2.1 and 16.1±2.1 vs.20.4±2.9,respectively,with statistically significant differences between the two groups(P<0.05).At the 6th month after treatment,there was no significant difference in NRS and ODI scores between the two groups(3.0±0.5 vs.3.2±0.6,21.4±2.0 vs.23.1±1.7).Compared with the base value,both groups showed significant reductions in NRS and ODI socres at the 1st,the 3rd,and the 6th months after treatment(P<0.001).Conclusion:Transforaminal epidural block can effectively alleviate discogenic low back pain and improve movement disorders.Transforaminal epidural combined with L2 nerve root pathway block is more effective than epidural block alone.

discogenic low back paintransforaminal epidural blocksinusvertebral nerves

李丽楠、刘巍、樊永冠、方叶、马迎存、刘波涛、司马蕾

展开 >

湖北文理学院附属医院 襄阳市中心医院疼痛科,襄阳 441021

安徽中医院大学附属太和中医院疼痛科,阜阳 236600

河北省沧州市中心医院疼痛科,沧州 061000

河南省中医院 河南中医药大学第二附属医院疼痛科,郑州 450002

中日友好医院疼痛科,北京 100029

展开 >

盘源性腰痛 经椎间孔硬膜外阻滞 窦椎神经

国家重点研发计划项目中日友好医院高水平医院临床业务费专项临床研究项目

2022YFC36022012022-NHLHCRF-YSPY-02

2024

中国疼痛医学杂志
北京大学,中华医学会疼痛学分会

中国疼痛医学杂志

CSTPCD北大核心
影响因子:1.457
ISSN:1006-9852
年,卷(期):2024.30(9)