Research progress on the involvement of the sympathetic nervous system in the pathogenesis of osteoporosis
Osteoporosis is a major bone health problem in the world,and the neural regulation of bone is the focus of current research. The effect of sympathetic nervous system on bone metabolism has been supported by a large number of research results,which is expected to bring breakthrough progress in the treatment of osteoporosis. It has been established that increased sympathetic nerve tone is harmful to bone quality and the microstructure and function of bone trabeculae. However,the precise mechanisms through which the sympathetic nervous system's contributes to the pathogenesis of osteoporosis remain unclear,and the specific mechanism of its effect on bone metabolism needs to be further clarified. This article reviews the role of the sympathetic nervous system in the pathogenesis of osteoporosis,summarizes the molecular mechanisms of the sympathetic nerve affecting osteoporosis,and investigates the role of the sympathetic nerve in different types of osteoporosis from different angles,thereby providing new insights for the prevention and treatment of osteoporosis.
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