Objective To analyze the application value of risk management in internal medicine.Methods Eight medical staff of the Department of Internal Medicine in Zaozhuang Yicheng District Yinping Town Center Health Hos-pital were selected as the study subjects,and routine management was used from June to December 2022 as the pre-implementation period,and risk management was used from January to June 2023 as the post-implementation period.The medical staff's knowledge of internal medicine risks,risk scores,and satisfaction were compared before and after the implementation of risk management.Results After the implementation of risk management,the medical staff's knowledge of internal medicine risks was higher than that before the implementation,and the difference was statisti-cally significant(P<0.05).After the implementation of risk management,the risk scores and satisfaction scores of the medical staff were higher than before the implementation,and the difference was statistically significant(both P<0.05).Conclusion Risk management has significant value in the management of internal medicine,which can not only improve and enhance the degree of internal medicine risk knowledge and risk awareness of medical staff in internal medicine,but also increase the satisfaction of medical staff.