首页|广东省育龄妇女生殖道沙眼衣原体感染时空分布及其社会经济影响因素

广东省育龄妇女生殖道沙眼衣原体感染时空分布及其社会经济影响因素

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目的 描述广东省育龄妇女生殖道沙眼衣原体(genital chlamydia trachomatis,GCT)感染的时空分布特征,探讨宏观社会经济因素对其影响.方法 收集广东省2014-2019 年育龄妇女GCT感染筛查结果 和相关宏观因素,基于泊松分布构建包含时间和空间项的贝叶斯时空层次模型,并使用嵌套拉普拉斯逼近(integrate nested Laplace approxima-tions,INLA)进行参数估计.结果 研究期间GCT感染时间变化趋势不明显,但具有显著空间聚集性.调整协变量和时间项后,高发地区集中在珠三角地区.各市区综合经济发展水平(RR=1.185,95%CI:1.117~1.257)、人口和交通水平(RR=1.058,95%CI:1.012~1.106)与GCT感染呈正相关,而医疗卫生水平与其呈负相关(RR=0.942,95%CI:0.924~0.960).结论 广东省育龄妇女GCT感染具有空间聚集性,社会经济因素与其感染密切相关.
Spatiotemporal Patterns of Genital Chlamydia Trachomatis Infections among Women of Childbearing Age and Impact of Social-economic Factors in Guangdong,China
Objective To describe the spatiotemporal patterns of genital chlamydia trachomatis(GCT)infections in Guangdong,and to explore social-economic factors associated with the risk of GCT infections.Methods Data of GCT infections among women of childbearing age in Guangdong province from 2014 to 2019 and social-economic factors were collected.Bayesian spatiotemporal hierarchy model with Poisson distribution was established including temporal and spatial terms.Integrate nested Laplace approximates(INLA)was used to estimate the parameters.Results GCT infections among women of childbearing age in Guangdong had no obviously temporal effect,but had significantly spatial heterogeneity.After adjusting for fixed covariate effects and temporal random effect,high-risk regions concentrated in Pearl Delta region.Comprehensive economic development(RR=1.185,95%CI:1.117~1.257)and population and transportation level(RR=1.058,95%CI:1.012~1.106)were positively associated with the prevalence of GCT infections,while the health service level had negatively association(RR=0.942,95%CI:0.924~0.960).Conclusion The prevalence of GCT infections among women of childbearing age shows spatial clustering characteristics.Social-economic factors are significantly related to the prevalence of GCT infections.

Genital chlamydia trachomatis infectionsSocial-economic factorsBayesian spatiotemporal hierarchy modelINLA

李瑞、熊文学、王文娟、周文愫、韩璐、凌莉

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中山大学公共卫生学院医学统计学系(510080)

国家卫生健康委员会男性生殖与遗传重点实验室

广东省生殖科学研究所(广东省生殖医院)

生殖道沙眼衣原体 社会经济因素 贝叶斯时空层次模型 嵌套拉普拉斯逼近

广东省医学科学技术研究基金项目

A2022314

2024

中国卫生统计
中国卫生信息学会 中国医科大学

中国卫生统计

CSTPCD北大核心
影响因子:1.172
ISSN:1002-3674
年,卷(期):2024.41(4)
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