Clinical analysis of nano-carbon used in single port laparo-scopic transanal total mesorectal resection for the treatment of low rectal cancer
朱郭婷 1周旋 2朱开梅3
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作者信息
1. 武汉大学人民医院神经外科(湖北 武汉 430060)
2. 武汉大学人民医院消化内科(湖北 武汉 430060)
3. 武汉大学人民医院胃肠外科(湖北 武汉 430060)
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摘要
目的:探究纳米炭在单孔腹腔镜经肛全直肠系膜切除术治疗低位直肠癌中的应用效果.方法:行单孔腹腔镜经肛全直肠系膜切除术患者96例,随机分为观察组(术前给予纳米炭混悬注射液)与对照组,每组48例.术后记录清扫的淋巴结数目,检测其中的黑染淋巴结数目,并行病理检测明确各淋巴结发生转移情况.结果:观察组检获淋巴结平均数目(18.46±3.52 vs 10.63±1.95)明显多于对照组(P＜0.05).观察组检出淋巴结发生转移率(12.19％)高于对照组(9.41％)(P＞0.05).黑染类淋巴结发生转移率(88/611,14.40％)明显高于未黑染(20/275,6.18％)与对照组(48/510,9.41％)(x2=9.007、6.495,P=0.003、0.011).结论:术前应用纳米活性炭混悬注射液,能够提高行单孔腹腔镜经肛全直肠系膜切除术患者淋巴结检获数目以及转移淋巴结检出率,可确保病理分期的准确性,在直肠癌临床治疗方面具有指导意义.
Abstract
Objective:To explore the application effect of nano-carbon in single port laparo-scopic transanal total mesorectal resection in the treatment of low rectal cancer.Methods:A total of 96 patients underwent single-port laparoscopic transanal mesorectal resection were selected and randomly divided into observation group(preoperative nano-carbon suspension injection)and control group,48 cases in each group based on the random number table method.After the operation,the number of lymph nodes dissected was recorded,and the number of dark-stained lymph nodes was detected,and pathological examination was performed to confirm the metastasis of each lymph node.Results:The average number of lymph nodes detected in the observation group(18.46±3.52 vs 10.63±1.95)was significantly higher than that in the control group,and the difference was statis-tically significant(P＜0.05).The rate of lymph node metastasis detected in the observation group(12.19％)was higher than that in the control group(9.41％),but the difference between the two groups was not statistically significant(P＞0.05).The metastasis rate of black-stained lymph nodes(88/611,14.40％)was significantly higher than that of non-stained lymph nodes(20/275,6.18％)and the control group(48/510,9.41％),and the difference was statistically significant(x2=9.007,6.495,P=0.003,0.011).Conclusion:Preoperative application of nano-activated carbon suspension injec-tion can increase the number of lymph nodes and the detection rate of lymph node metastasis in pa-tients undergoing single-port laparoscopic transanal mesorectal resection,which can ensure the ac-curacy of pathological staging.It can be used in clinical rectal cancer.The treatment is of guiding sig-nificance.
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