Clinical characteristics and related factors of colorectal polyps in young population
Objective:To analyze the characteristics of onset and related risk factors of colorectal polyps in young people,and to provide scientific basis for the prevention,early screening,and treatment of this population. Methods:A total of 443 patients aged ≤40 years,who under-went electronic colonoscopy at the Gastrointestinal Endoscopy Center of Beijing Friendship Hospital,Capital Medical University,were collected. Among them,223 cases were included in the colorectal polyp group,and 220 cases were included in the normal control group. The clinical and pathological characteristics of colorectal polyps in young people were summarized,and the related factors of colorectal polyps in young people were analyzed,compared the differences between the two groups in aspects such as gender,weight,height,body mass index (BMI),smoking,drinking,triglycerides (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C),blood uric acid (UA),fasting blood glucose (FBG),and carcino-embryonic anti-gen (CEA). Results:A total of 412 polyps were detected and biopsied. The incidencerate of colorectal polyps was higher in males,with the majority of patients presented as asymptomatic. Most polyps were multiple,with the highest incidence rate of 2-5 polyps,mainly in the range of 0.6-0.9 cm in diameter. The sigmoid colon be the most common site,and the main morphology was flat (Yamada type Ⅰ). The pathological types were predominantly hyperplastic,adenomatous,and inflam-matory polyps. The occurrence of colorectal polyps in young adults was correlated with gender,smoking,alcohol,height,BMI,TC,LDL-C,HDL-C,UA,and CEA (P<0.05);alcohol consumption and CEA were independent risk factors for colorectal polyps in young people (P<0.05). Conclusion:The detection rate of colorectal polyps in youth population is on the rise,influenced by a variety of factors,and it is important to pay attention to the health examination of colonoscopy,especially for high-risk young groups. At the same time,strengthen early screening and health education.
万方数据
维普
