Objective To explore wound repair strategies for Marjolin's ulcer.Methods A retro-spective analysis was conducted on the clinical data of 38 patients with Marjolin's ulcer who were treated in our department over the past 10 years.Clinical data analysis,radiopathological diagnosis evaluation,and descrip-tion of surgical methods were performed.Outcome measures included surgical approaches,wound healing sta-tus,tumor recurrence,and survival rate.Results Among the 38 patients,there were 23 males and 15 fe-males,with a mean age of(53.63±9.74)years.The causes of the burns were flame burns in 32 cases and scald burns in 6 cases,with a mean latent period of(35.65±14.60)years.The lesions were located in the head(7 cases),lower limbs(18 cases),upper limbs(8 cases),trunk(3 cases),and face(2 cases).Pathological examination revealed 2 cases of basal cell carcinoma(superficial phenotype 1 case,infiltrating type 1 case;pathological grading:moderately differentiated 1 case,and highly differentiated 1 case)and 36 cases of squamous cell carcinoma(pathological grading:poorly differentiated 2 cases,moderately differentiated 10 cases,and highly differentiated 24 cases).Among them,35 patients underwent surgical treatment,with 6 patients undergoing amputation.Wound repair strategies included skin grafting(19 cases),local flaps(4 cases),and free flap transfer(6 cases).The median follow-up time was 2(2,3)years.30 patients had good wound healing without tumor recurrence,while 5 patients experienced tumor recurrence,with 3 undergoing subsequent surgical treatment.One patient died during the follow-up period,and 3 patients opted out of treatment and died during the follow-up period.Conclusion Wound repair strategies for Marjolin's ulcer should be personalized based on the tumor's location,nature,extent,and the overall condition of the patient,with early excision of the lesion being the key to treatment.Methods such as skin grafting,flap transfer,free flap transplantation,and amputa-tion can be used to repair the wound caused by Marjolin's ulcer.Surgical treatment can promote wound healing,but tumor recurrence remains a significant issue that requires further research and exploration.
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