Objective To discuss the efficacy and safety of endovascular intervention via transradial approach(TRA)in the treatment of acute ischemic stroke(AIS).Methods A total of 113 AIS patients un-derwent intra-arterial thrombolytic therapy from January 2021 to January 2023 were retrospectively analyzed.According to the surgical approaches,all patients were divided into the study group(n=57)and the control group(n=56),and received endovascular intervention via TRA and via transfemoral approach(TFA)respec-tively.The perioperative indexes,hemorheology indexes,clinical efficacy,and complications were compared between the two groups.Results All operations were accomplished successfully.The success rate of puncture was 100％and 96.64％in the study group and control group respectively,but there was no significant difference in the puncture time,time to reach the occluded vessel,operation time,success rate of puncture and vascular recanalization rate between the two groups(P＞0.05).The hemorheology indexes(high shear viscosity,low shear viscosity and plasma specific viscosity)were significantly lower in both groups after operation than those before operation(P＜0.05),however,no statistical difference was observed between the two groups,both preoperatively and postoperatively(P＞0.05).According to NIHSS score,the clinical efficacy revealed that significant improvement in 30 cases,improvement in 22 cases,and failure in 5 cases in the study group,and significant improvement in 29 cases,improvement in 20 cases,and failure in 7 cases in the control group 6 months after the operation,and there was no significant difference in the total clinical effective rate between the two groups(91.23％vs.87.50％,P＞0.05).The radial artery spasm occurred in 1 case during the surgery,and forearm hematoma and intracranial hemorrhage occurred in 1 case respectively after the surgery in the study group without bleeding of puncture site,while puncture site bleeding was found in 10 cases,and intracranial hemorrhage was in 2 cases in the control group,and a statistical difference was observed in com-plication rate between the two groups(5.26％vs.21.43％,P＜0.05).Conclusions The endovascular intervention via TRA is safe for AIS,and it can achieve a similar clinical efficacy as TFA,and effectively reduce the incidence of complications.TRA can be preferred for the AIS patients with the indications.
万方数据
维普
