中国现代医学杂志2024,Vol.34Issue(1) :65-71.DOI:10.3969/j.issn.1005-8982.2024.01.010

血脂波动性与心血管疾病的研究进展

Research progress of the correlation between lipid variability and cardiovascular diseases

张迷磊 戴霞 杨琼 陈海燕 莫彬彬
中国现代医学杂志2024,Vol.34Issue(1) :65-71.DOI:10.3969/j.issn.1005-8982.2024.01.010

血脂波动性与心血管疾病的研究进展

Research progress of the correlation between lipid variability and cardiovascular diseases

张迷磊 1戴霞 1杨琼 1陈海燕 1莫彬彬1
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作者信息

  • 1. 广西医科大学第一附属医院, 广西 南宁 530021
  • 折叠

摘要

血脂异常在心血管疾病(CVD)的进程中起重要作用.血脂波动性是一项重要的新型评估参数.近年来,大量国内外研究证实,除了平均血脂水平之外,标准差、变异系数及与均值无关的波动性等指标评价的个体血脂参数的波动性与CVD不良健康结局独立相关,维持血脂长期稳定的管理策略在延缓疾病进程中起着关键作用.该综述旨在总结血脂参数的波动性在CVD相关的研究进展及其在临床诊断和管理决策中的应用价值.

Abstract

Dyslipidemia is a significant factor in the progression of cardiovascular diseases(CVD).Recent studies have shown that lipid fluctuations are linked to unfavorable clinical outcomes,highlighting the importance of long-term stable lipid management strategies in delaying the disease process.Moreover,lipid variability has emerged as an important new assessment parameter.Apart from mean lipid levels,the correlation between individual blood lipid variation and CVD,evaluated by metrics such as standard deviation(SD),coefficient of variation(CV),and variability independent of the mean(VIM),has been well confirmed.This review aims to summarize the research progress on the variability of blood lipid parameters in CVD.The review also highlights the clinical significance of these parameters in the diagnosis and management of these diseases.

关键词

心血管疾病/血脂波动性/综述

Key words

cardiovascular disease/lipid variability/review

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基金项目

国家自然科学基金(82160440)

广西医科大学第一附属医院护理临床研究攀登计划(YYZS2020028)

出版年

2024
中国现代医学杂志
中南大学,卫生部肝胆肠外科研究中心

中国现代医学杂志

CSTPCD
影响因子:0.927
ISSN:1005-8982
参考文献量2
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