Objective To analyze the impact of Vitapex paste and metronidazole iodine paste on the efficacy of root canal treatment in patients with sinus tract-type apical periodontitis.Methods A total of 118 patients diagnosed with sinus tract-type apical periodontitis at Qingdao Hai Ci Hospital affiliated with Qingdao University from January 2019 to February 2022 were selected.Using a random number table,the patients were divided into a study group and a control group,with 59 patients in each group.Both groups underwent root canal treatment,with the control group filled with metronidazole iodine paste and the study group filled with Vitapex paste.Follow-up was conducted for 6 months after treatment.The post-filling pain reaction,sinus tract healing,apical healing,comprehensive efficacy,and levels of periodontal inflammatory factors(high-sensitivity C-reactive protein,interleukin-6,interleukin-8)were compared between the two groups.Results The incidence of post-filling pain reactions was comparable between the two groups(P>0.05).The study group showed a higher sinus tract healing rate than the control group(P<0.05).The root apex transparency area at different time points showed differences(P<0.05)and the study group had a lower root apex transparency area at 3 and 6 months compared to the control group(P<0.05).The change trend in the root apex transparency area differed between the two groups(P<0.05).The success rate in the study group was higher than in the control group(P<0.05).The changes in high-sensitivity C-reactive protein,interleukin-6,and interleukin-8 values before and after treatment were higher in the study group than in the control group(P<0.05).Conclusion Compared to metronidazole iodine paste,Vitapex paste demonstrated superior advantages in sinus tract healing,apical healing,and reduction of periodontal inflammatory responses in patients with sinus tract-type apical periodontitis undergoing root canal treatment.The overall treatment effect was better with Vitapex paste.
维普
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