Gold nanoparticles(AuNPs)are one of the most commonly used nanomaterials in various medical applications.Using AuNPs as carriers can accurately deliver drugs to target tissues or cells,which can be helpful in improving the efficiency of disease diagnosis and treatment.Photodynamic therapy(PDT)is a newly approved clinical strategy and has a great potential for treating tumors.Evidence suggests that photosensitizer(PS)can be loaded on AuNPs through interactions with covalent or non-covalent bonds,which not only promotes the effective uptake of PS into tumor cells and improves the efficacy of PDT,but also overcomes limitations brought about by applying PDT alone.This review focuses on the types,properties and applications of AuNPs,and the anticancer activity of AuNPs combined with PDT is emphatically introduced.