In recent years,the landscape of cancer treatment has been transformed by the advent of immunotherapy.However,the effectiveness of single-agent immunotherapy remains relatively limited.Combining immunotherapy with chemotherapy or targeted therapy has emerged as a strategy to achieve a synergistic antitumor effect by modulating the tumor microenvironment.Amino acid metabolism,particularly taurine metabolism,holds the promise of enhancing the efficacy of immunotherapy through metabolic reprogramming of the microenvironment.This article specifically delves into the potential mechanisms through which taurine regulates the tumor microenvironment and tumor cell metabolism,with the aim of offering novel insights into tumor immunotherapy.
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