Objective To investigate the correlation between Young's modulus obtained from endorectal shear wave elastography(SWE)and lymph node metastasis in rectal cancer,explore the predictive value of endorectal ultrasound(ERUS)combined with SWE for lymph node metastasis in rectal cancer,and validate its diagnostic accuracy for T staging of rectal cancer.Methods A retrospective analysis was conducted on the clinical data of 53 patients with moderately differentiated adenocarcinoma of rectal ulcer type admitted to Inner Mongolia Autonomous Region People's Hospital from November 2021 to November 2022.All patients underwent preoperative ERUS and SWE examination,and the average Young's modulus value(Emean)of the lesion was measured.According to postoperative pathology as the gold standard and based on whether lymph node metastasis occurred,patients were divided into the lymph node metastasis group and the non-lymph node metastasis group.Point-biserial correlation analysis was used to analyze the correlation between lymph node metastasis and Emean value.Based on Emean value,Logistic regression,random forest model,and support vector machine model were used to further verify the diagnostic effect of SWE on T staging of rectal cancer.Results Lymph node metastasis of rectal cancer was positively correlated with the Emean value of the lesion(rs = 0.752,P＜0.05),and there was a statistically significant difference in Emean values between the lymph node metastasis group and the non-lymph node metastasis group(P＜0.05).The accuracy of ERUS in diagnosing T staging of rectal cancer was 71.70%,while the accuracy of ERUS combined with SWE in diagnosing T staging of rectal cancer was 86.79%.There were statistically significant differences in Emean values among different T stages of rectal cancer(P＜0.05).Conclusion ERUS combined with SWE has high predictive value for lymph node metastasis in rectal cancer,and it can also improve the diagnostic accuracy of T staging of rectal cancer.
维普
万方数据