Inflammatory bowel disease is a chronic inflammatory and immune-related intestinal disease and represents a major global health challenge with its incidence being on the rise year by year.However,the exact pathogenesis of inflammatory bowel disease is still not well understood.AMP-activated protein kinase(AMPK)is a highly conserved cellular energy sensor that plays a crucial role in maintaining energy balance within the body.In recent years,studies have found that AMPK can slow down the progression of inflammatory bowel disease by enhancing intestinal barrier function,inhibiting inflammatory responses,exerting anti-fibrosis effects,and promoting autophagy.This review will explore the aforementioned perspectives,with the aim of providing novel insights into therapeutic targets for inflammatory bowel disease.
inflammatory bowel diseaseAMP-activated protein kinasecolitis
国家科技期刊平台
NSTL
维普
万方数据
