Organ fibrosis is the result of overrepair after tissue damage,and is associated with organ failure and high mortality.Therefore,it is of great value to find effective treatment methods for fibrosis.In recent years,it has been found that mesenchymal stem cells-derived exosomes have the advantages of smaller size,low immunogenicity and no tumorigenic effect,showing a good application prospect in anti-fibrosis.This article reviews the mechanism of treating various organ fibrosis with mesenchymal stem cells-derived exosomes.
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