Embryo implantation failure may be associated with circadian disturbances.Studies have shown that the human physiological function and metabolic activities are regulated by the circadian rhythm,and this rhythm disturbance may negatively affect the reproductive system function.Circadian rhythm disorder can lead to abnormal hormone secretion,disturbed immune function and imbalance of cell cycle regulation,all of which may affect the state of the endometrium and the process of embryo implantation.Therefore,maintaining a good circadian rhythm is crucial for successful embryo implantation.Here,we aimed to explore the correlation between circadian rhythm and embryo implantation failure,based on which conditioning was performed to provide more effective treatment strategies for patients with recessive abortion,thus improving the chance of successful embryo implantation.
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