Objective To explore the effects of thromboelastography (TEG)-guided blood transfusion therapy on perioperative clinical parameters in tumor patients.Methods A total of 138 tumor patients requiring surgical treatment at the 903 Hospital of the Joint Logistics Support Force of the People's Liberation Army of China from January 2019 to January 2024 were recruited.Participants were divided into a treatment group and a control group via the random number table method,with 69 cases in each group.The patients in the treatment group were monitors for the blood coagulation status using TEG,based on which personalized transfusion strategies were adopted.In contrast,the patients in the control group were managed according to standard transfusion practices.The usage of blood products,coagulation function indicators,blood routine indicators,TEG parameters,postoperative blood loss,and length of hospital stays were compared between the two groups.Results The treatment group used fewer fresh frozen plasma,suspended red blood cells,cryoprecipitated antihemophilic factors,and platelets compared to the control group (P<0.05).The prothrombin time and the activated partial thromboplastin time were shorter and the level of fibrinogen was lower in the treatment group compared with the control group (P<0.05),while the thrombin time in the treatment group was longer than that in the control group (P<0.05).The differences in the hematocrit,platelet count,and hemoglobin levels before and after treatment were higher in the treatment group than in the control group (P<0.05).The alpha-angle,lysis at 30 minutes,and maximum amplitude in the treatment group were greater than those in the control group (P<0.05),whereas the K time and reaction time in the treatment group were shorter than those in the control group (P<0.05).The treatment group had less postoperative blood loss and shorter length of hospital stays compared with the control group (P<0.05).Conclusions In tumor patients,the application of TEG-guided transfusion strategies during the perioperative period significantly optimizes the use of blood products and improves coagulation profiles and clinical recovery indicators.
关键词
输血治疗/血栓弹力图/肿瘤/临床参数/围手术期
Key words
blood transfusion therapy/thromboelastography/tumor/clinical parameters/perioperative period
维普
万方数据