Study on the anesthetic effect of paravertebral nerve block during laparoscopic radical surgery for gastric cancer
Objective To analyze the impact of different anesthesia schemes on the anesthetic effect and prognosis of patients with laparoscopic radical surgery for gastric cancer.Methods A total of 50 patients with laparoscopic radical surgery for gastric cancer were divided into a reference group and a control group according to the order of admission and treatment,with 25 cases in each group.The control group received general anesthesia,and the reference group received general anesthesia + paravertebral nerve block anesthesia.Both groups were compared in terms of anesthesia,blood oxygen index in different time periods,hormone level before and after intubation,occurrence of adverse reactions,anesthetic dosage and pain score in different states.Results The extubation time in the control group was(25.58±1.42)min,and the duration of stay in monitoring treatment room after anesthesia was(58.47±1.58)min;the extubation time in the reference group was(11.84±1.16)min,and the stay time in the monitoring treatment room after anesthesia was(41.82±1.14)min.The extubation time and the stay time in the monitoring treatment room after anesthesia in the reference group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After 15 min of surgery,the mean arterial pressure and heart rate in the reference group were(85.26±1.71)mm Hg(1 mm Hg= 0.133 kPa)and(55.85±1.35)beats/min,which were lower than those of(88.21±1.55)mm Hg and(60.79±0.55)beats/min in the control group,respectively.The difference was statistically significant(P<0.05).After surgery,there was no statistically significant difference in mean arterial pressure and heart rate between the two groups(P>0.05).Before intubation,there was no statistically significant difference in epinephrine and norepinephrine between the two groups(P>0.05).Immediately after intubation,the epinephrine of(72.64±1.25)pmol/L in the reference group was higher than that of(59.54±1.53)pmol/L in the control group,and the norepinephrine of(264.45±0.39)pmol/L was lower than that of(278.77±0.54)pmol/L in the control group.The difference was statistically significant(P<0.05).The incidence of adverse reactions in the reference group was 4.00%,which was lower than that of 28.00%in the control group,and the difference was statistically significant(P<0.05).In the control group,the dosage of propofol was(56±12)mg,the dosage of remifentanil was(116±14)μg,the dosage of sufentanil was(130±12)μg;in the reference group,the dosage of propofol was(41±10)mg,the dosage of remifentanil was(80±6)μg and the dosage of sufentanil was(94±10)μg.The dosage of propofol,remifentanil and sufentanil in the reference group were lower than those in the control group,and the difference was statistically significant(P<0.05).Immediately after intubation,the pain scores in resting state and cough state in the reference group were(1.86±0.32)and(1.45±0.25)points,respectively,which were lower than those of(4.63±0.21)and(3.56±0.16)points in the control group,and the difference was statistically significant(P<0.05).Conclusion Paravertebral nerve block anesthesia is required to reduce the dosage of anesthetic drugs and reduce the impact on the prognosis of patients during laparoscopic radical surgery for gastric cancer,which not only reduces the intraoperative pain of patients,but also speeds up the recovery of patients.It is worthy of extensive reference from medical institutions at all levels.
NETL
NSTL
万方数据
维普
