首页|内镜下黏膜切除术治疗胃肠道息肉的手术效果及对患者胃肠道激素水平的影响研究

内镜下黏膜切除术治疗胃肠道息肉的手术效果及对患者胃肠道激素水平的影响研究

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目的 探究内镜下黏膜切除术治疗胃肠道息肉的手术效果及对患者胃肠道激素水平的影响。方法 100 例胃肠道息肉患者,按照随机数字排列表法分为干预组与参照组,每组 50 例。干预组给予内镜下黏膜切除术治疗,参照组给予普通内镜下电凝切除术治疗。比较两组息肉切除率(整块切除率、完整切除率),术后恢复情况(术后 3 d平均体温、术后 1 d白细胞计数、术后进食时间、术后住院时间),手术前后血清炎症因子(C反应蛋白、降钙素原)水平及术后并发症发生情况。结果 干预组息肉整块切除率 98。00%、完整切除率 100。00%均高于参照组的 84。00%、92。00%,差异有统计学意义(P<0。05)。两组术后 3 d平均体温、术后 1 d白细胞计数比较,差异无统计学意义(P>0。05);干预组术后进食时间(2。96±0。72)d、术后住院时间(5。23±1。15)d均短于参照组的(3。87±0。98)、(6。82±2。03)d,差异有统计学意义(P<0。05)。手术前,两组血清C反应蛋白及降钙素原水平比较,差异无统计学意义(P>0。05)。手术后,干预组血清C反应蛋白(53。60±6。08)mg/L、降钙素原(0。47±0。11)ng/ml均低于参照组的(72。96±8。55)mg/L、(0。79±0。18)ng/ml,差异有统计学意义(P<0。05)。干预组术后并发症发生率(6。00%)低于参照组(20。00%),差异有统计学意义(P<0。05)。结论 对胃肠道息肉患者使用内镜下黏膜切除术诊治有利于提高整体诊治效果,降低机体炎症反应及术后并发症发生风险,具有临床应用价值,提倡使用。
Study on the surgical effect of endoscopic mucosal resection for gastrointestinal polyps and its impact on gastrointestinal hormone levels in patients
Objective To investigate the surgical effect of endoscopic mucosal resection for gastrointestinal polyps and its impact on gastrointestinal hormone levels in patients.Methods 100 patients with gastrointestinal polyps were divided into an intervention group and a reference group according to random number arrangement table,with 50 cases in each group.The intervention group was given endoscopic mucosal resection,and the reference group was given general endoscopic electroresection.Comparison was made on polypectomy rates(whole resection rate and complete resection rate),postoperative recovery(average body temperature 3 d after surgery,white blood cell count 1 d after surgery,postoperative eating time,postoperative hospital stay),serum inflammatory factor levels(C-reactive protein and procalcitonin)before and after surgery,and postoperative complications.Results The whole resection rate and complete resection rate of polyps were 98.00%and 100.00%in the intervention group,which were higher than those of 84.00%and 92.00%in the reference group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in average body temperature 3 d after surgery and white blood cell count 1 d after surgery between the two groups(P>0.05).The postoperative eating time of(2.96±0.72)d and postoperative hospital stay of(5.23±1.15)d in the intervention group were shorter than those of(3.87±0.98)and(6.82±2.03)d in the reference group,and the difference was statistically significant(P<0.05).Before surgery,there was no statistically significant difference in serum C-reactive protein and procalcitonin levels between the two groups(P>0.05).After surgery,the serum C-reactive protein of(53.60±6.08)mg/L and procalcitonin of(0.47±0.11)ng/ml in the intervention group were lower than those of(72.96±8.55)mg/L and(0.79±0.18)ng/ml in the reference group,and the difference was statistically significant(P<0.05).The incidence of postoperative complications in the intervention group(6.00%)was lower than that in the reference group(20.00%),and the difference was statistically significant(P<0.05).Conclusion Endoscopic mucosal resection in the diagnosis and treatment of patients with gastrointestinal polyps is beneficial to improve the overall diagnosis and treatment effect and reduce the risk of inflammation and postoperative complications.It has clinical application value and should be recommended.

Gastrointestinal polypsEndoscopic mucosal resectionElectroresectionGastrointestinal hormone

王小英、邓大一

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201800 上海市嘉定区中医医院外科

胃肠道息肉 内镜下黏膜切除术 电凝切除术 胃肠道激素

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(1)
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