Study on effect of rSO2-BIS target-oriented anesthesia management on postoperative cognitive function of patients with non-acute fragile brain function
Objective To observe the effect of regional cerebral oxygen saturation(rSO2)-bispectral index(BIS)target-oriented anesthesia management on postoperative cognitive function of patients with non-acute fragile brain function.Methods A total of 70 patients with non-acute fragile brain function were divided into a control group and an experimental group according to different anesthesia management methods,with 35 cases in each group.The control group received BIS target-oriented anesthesia management,and the experimental group received rSO2-BIS target-oriented anesthesia management.Both groups were compared in terms of hemodynamic parameters at different time points,cognitive function,visual analogue scale(VAS)scores before anesthetic induction(T0)and 2 d after surgery(T5),and the incidence of complications.Results At T0,there was no statistically significant difference in heart rate and mean arterial pressure between the two groups(P>0.05).Compared with those at T0,the heart rate and mean arterial pressure of the two groups were decreased after anesthesia induction(T1),immediately after intubation(T2),at the time of incision(T3),and at the end of surgery(T4),but the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).The incidence of postoperative delirium(POD)of 5.71%in the experimental group was lower than that of 22.86%in the control group,and the POD duration of(16.5±0.7)h was shorter than that of(20.5±1.4)h in the control group.The differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of postoperative cognitive dysfunction(POCD)between the two groups(P>0.05).At T5,the VAS score in both groups was higher than that at T0,but VAS score of(3.43±0.08)points in the experimental group was lower than that of(5.13±0.11)points in the control group.The differences were statistically significant(P<0.05).The complication rate of 5.71%in the experimental group was lower than that of 22.86%in the control group,and the difference was statistically significant(P<0.05).Conclusion The effect of rSO2-BIS target-oriented anesthesia management in patients with non-acute fragile brain function is significantly better than that of BIS target-oriented anesthesia management.
Regional cerebral oxygen saturationBispectral indexTarget-oriented anesthesia managementNon-acute fragile brain function
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