首页|红霉素眼膏联合耳穴贴压治疗儿童急性结膜炎的疗效分析

红霉素眼膏联合耳穴贴压治疗儿童急性结膜炎的疗效分析

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目的 分析红霉素眼膏联合耳穴贴压治疗儿童急性结膜炎的疗效。方法 80 例急性结膜炎患儿,根据随机数字表法分为研究组和对照组,各 40 例。对照组采用红霉素眼膏治疗,研究组在对照组基础上加用耳穴贴压治疗。比较两组临床疗效、不良反应发生情况以及治疗前后眼部症状(眼痛、异物感、流泪、分泌物、畏光)评分、炎性因子[白细胞介素-6(IL-6)、C反应蛋白(CRP)、单核细胞趋化蛋白-1(MCP-1)]水平。结果 研究组治疗总有效率 95。00%高于对照组的 80。00%(P<0。05)。治疗后,两组患儿眼痛、异物感、流泪、分泌物、畏光评分均较治疗前降低,且研究组患儿眼痛评分(0。61±0。08)分、异物感评分(0。47±0。11)分、流泪评分(0。38±0。05)分、分泌物评分(0。62±0。18)分、畏光评分(0。42±0。13)分均低于对照组的(0。97±0。24)、(0。73±0。18)、(0。85±0。13)、(0。96±0。21)、(0。85±0。23)分(P<0。05)。治疗后,两组患儿IL-6、CRP、MCP-1 水平均较治疗前降低,且研究组患儿IL-6(5。24±1。27)ng/L、CRP(2。27±0。54)mg/L、MCP-1(65。38±9。47)pg/ml均低于对照组的(8。26±1。66)ng/L、(4。05±0。26)mg/L、(75。48±9。32)pg/ml(P<0。05)。结论 红霉素眼膏联合耳穴贴压可进一步提高儿童急性结膜炎的治疗效果,改善患儿临床症状,抑制眼部炎症反应,安全可靠。
Analysis of curative effect of erythromycin eye ointment combined with auricular acupoint sticking on children with acute conjunctivitis
Objective To analyze the effect of erythromycin eye ointment combined with auricular acupoint sticking on children with acute conjunctivitis.Methods A total of 80 children with acute conjunctivitis were divided into a study group and a control group according to random number table method,each with 40 cases.The control group was treated with erythromycin eye ointment,and the study group was treated with auricular acupoint sticking on the basis of the control group.Both groups were compared in terms of clinical efficacy,occurrence of adverse reactions,ocular symptom scores(eye pain,foreign body sensation,tearing,secretion,photophobia)and the levels of inflammatory factors[interleukin-6(IL-6),C-reactive protein(CRP)and monocytochemotactic protein-1(MCP-1)]before and after treatment.Results The total effective rate of 95.00%in the study group was higher than that of 80.00%in the control group(P<0.05).After treatment,the scores of ocular symptoms(eye pain,foreign body sensation,weep,secretion,photophobia)in both groups were lower than those before treatment in this group;in the study group,the score of eye pain was(0.61±0.08)points,the score of foreign body sensation was(0.47±0.11)points,the score of tearing was(0.38±0.05)points,the score of secretion was(0.62±0.18)points,the score of photophobia was(0.42±0.13)points,which were lower than those of(0.97±0.24),(0.73±0.18),(0.85±0.13),(0.96±0.21)and(0.85±0.23)points in the control group(P<0.05).After treatment,the levels of IL-6,CRP and MCP-1 in both groups were lower than those before treatment in this group;the study group had IL-6 of(5.24±1.27)ng/L,CRP of(2.27±0.54)mg/L and MCP-1 of(65.38±9.47)pg/ml,which were lower than those of(8.26±1.66)ng/L,(4.05±0.26)mg/L and(75.48±9.32)pg/ml in the control group(P<0.05).Conclusion Erythromycin eye ointment combined with auricular acupoint sticking can further improve the therapeutic effect of acute conjunctivitis in children,improve the clinical symptoms of children,inhibit eye inflammation.It is safe and reliable.

Erythromycin eye ointmentAuricular acupoint stickingAcute conjunctivitis in childrenInflammatory factorsEye symptoms

杨红平、胡军华

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338000 新余市妇幼保健院五官科

338000 新余市人民医院眼科

红霉素眼膏 耳穴贴压 儿童急性结膜炎 炎性因子 眼部症状

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(1)
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