Comparison of efficacy of single-port and double-port laparoscopic hernioplasty for inguinal hernia in children
Objective To compare the efficacy of single-port and double-port laparoscopic hernioplasty for inguinal hernia in children.Methods A total of 150 children with inguinal hernia were randomly divided into a control group and an observation group,with 75 cases in each group.The patients in the control group were treated with double-port laparoscopic hernioplasty,while the patients in the observation group were treated with single-port laparoscopic hernioplasty.Comparison was made on perioperative indexes(amount of bleeding,off-bed activity time,operation time,time of hospitalization),serum stress response[norepinephrine(NE),aldosterone(ALD),cortisol(Cor)]and serum pain mediators[β-endorphin(β-EP),substance P(SP),serotonin(5-HT)]before and after treatment between the two groups.Results The amount of bleeding of(4.31±0.39)ml in the observation group was less than(6.42±0.47)ml in the control group;the off-bed activity time of(3.52±0.28)h and time of hospitalization of(1.51±0.09)d in the observation group were shorter than(5.31±0.34)h and(2.02±0.18)d in the control group;the operation time of(39.87±3.38)min in the observation group was longer than(32.33±2.87)min in the control group(P＜0.05).After treatment,β-EP level in both groups was lower than that before treatment,SP and 5-HT levels were higher than those before treatment;β-EP of(108.44±6.54)ng/ml in the observation group was higher than(78.29±5.35)ng/ml in the control group;SP of(87.66±7.11)pg/ml and 5-HT of(288.83±13.25)nmol/L in the observation group were lower than(103.55±8.44)pg/ml and(365.87±16.95)nmol/L in the control group(P＜0.05).Conclusion Compared with double-port laparoscopic hernioplasty for inguinal hernia in children,single-port laparoscopic hernioplasty is more time-consuming,but the overall perioperative parameters are better,the levels of serum stress response and serum pain mediators are lower after operation,and the clinical application value is significant.
万方数据
维普
