首页|小剂量罗哌卡因复合羟考酮用于老年下肢骨折手术麻醉中的效果探讨

小剂量罗哌卡因复合羟考酮用于老年下肢骨折手术麻醉中的效果探讨

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目的 探讨小剂量罗哌卡因复合羟考酮应用于老年下肢骨折手术麻醉中的效果。方法 回顾性分析接受下肢骨折手术治疗的 80 例老年患者的临床资料,按麻醉方式不同分为对照组及观察组,每组 40 例。对照组采用常规剂量罗哌卡因麻醉,观察组采用小剂量罗哌卡因复合羟考酮麻醉。比较两组患者的血流动力学指标(收缩压、舒张压、心率)变化情况,麻醉质量,术后疼痛情况,不良反应发生情况。结果 麻醉后 5、30 min,两组收缩压、舒张压、心率水平均下降,但观察组的收缩压、舒张压、心率水平高于对照组,变化幅度小于对照组(P<0。05)。观察组麻醉优良率为 95。00%(38/40),对照组为 97。50%(39/40),对比差异不显著(P>0。05)。观察组术后 2、6 h疼痛数字评分法(NRS)评分分别为(2。82±0。52)、(3。37±0。44)分,低于对照组的(3。58±0。54)、(4。10±0。51)分(P<0。05);两组术后 12 h NRS评分对比,差异不显著(P>0。05)。观察组不良反应发生率为 10。00%(4/40),低于对照组的 25。00%(10/40),但组间对比差异不显著(P>0。05)。结论 小剂量罗哌卡因复合羟考酮应用于老年下肢骨折手术中取得了良好的麻醉效果,能维持血流动力学的稳定,提升术后镇痛效果,并且有良好的安全性。
Effect of low-dose ropivacaine combined with oxycodone in anesthesia of lower extremity fracture surgery in elderly patients
Objective To discuss the effect of low-dose ropivacaine combined with oxycodone in anesthesia of lower extremity fracture surgery in elderly patients.Methods The clinical data of 80 elderly patients undergoing surgical treatment for lower extremity fracture were retrospectively analyzed and divided into a control group and an observation group according to different anesthesia methods,with 40 cases in each group.The control group was anesthetised with conventional dose of ropivacaine,and the observation group was anesthetised with low dose of ropivacaine combined with oxycodone.The changes of hemodynamic indexes(systolic blood pressure,diastolic blood pressure,heart rate),anesthesia quality,postoperative pain,and occurrence of adverse reactions were compared between the two groups.Results At 5 and 30 min after anesthesia,the systolic blood pressure,diastolic blood pressure and heart rate decreased in both groups,but the systolic blood pressure,diastolic blood pressure and heart rate in the observation group were higher than those in the control group,and the change range was smaller than that in the control group(P<0.05).The excellent and good rate of anesthesia was 95.00%(38/40)in the observation group and 97.50%(39/40)in the control group,with no significant difference(P>0.05).The numerical rating scale(NRS)scores of the observation group were(2.82±0.52)and(3.37±0.44)points at 2 and 6 h after surgery,which were lower than(3.58±0.54)and(4.10±0.51)points of the control group(P<0.05).There was no significant difference in NRS score at 12 h after surgery between the two groups(P>0.05).The incidence of adverse reactions in the observation group was 10.00%(4/40),which was lower than 25.00%(10/40)in the control group,but there was no significant difference between the two group(P>0.05).Conclusion The application of low-dose ropivacaine combined with oxycodone in lower extremity fracture surgery in the elderly has achieved good anesthetic effect,and can maintain the stability of hemodynamics,improve the postoperative analgesia effect,and has high safety.

Lower extremity fracture surgeryLow-doseRopivacaineOxycodoneAnesthesia quality

高静丹、濮健峰

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215500 常熟市第二人民医院麻醉科

下肢骨折手术 小剂量 罗哌卡因 羟考酮 麻醉质量

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(2)
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