Clinical retrospective analysis of 60 cases of acute infectious laryngitis in children
Objective To analyze the effectiveness and feasibility of budesonide aerosol inhalation therapy for children with acute infectious laryngitis.Methods The clinical data of 60 children with acute infectious laryngitis was retrospectively analyzed.According to different aerosol treatment regimen,they were divided into an observation group and a control group,with 30 cases in each group.The observation group was given atomized inhalation of budesonide,and the control group was given atomized inhalation of dexamethasone.The clinical effects,duration of clinical symptoms,incidence of adverse drug reactions and inflammatory indicators before and after treatment were compared between the two groups.Results The total effective rate of the observation group was 93.33%(28/30),which was significantly higher than 73.33%(22/30)of the control group,and the difference was statistically significant(P＜0.05).The duration of laryngeal stridor,barking cough,dyspnea,hoarseness and fever of the observation group were(3.77±1.21),(3.28±1.06),(1.78±0.57),(4.36±0.56)and(1.48±0.48)d,which were shorter than(4.65±1.26),(4.77±1.21),(2.91±0.99),(5.45±0.49)and(2.56±0.78)d of the control group,and the difference was statistically significant(P＜0.05).After treatment,the hypersensitive C-reactive protein(hs-CRP)level in both groups was significantly lower than that before treatment,and the hs-CRP level of(7.86±2.13)mg/L in the observation group was lower than(12.67±2.75)mg/L in the control group.The difference was statistically significant(P＜0.05).The incidence of adverse drug reactions of 6.67%in the observation group was lower than 26.67%in the control group,and the difference was statistically significant(P＜0.05).Conclusion Budesonide aerosol inhalation therapy for children with acute infectious laryngitis has an ideal effect,which can significantly improve the clinical symptoms of children and shorten the duration of clinical symptoms.At the same time,it is safe and has important clinical application value.
BudesonideAerosol inhalationDexamethasoneAcute infectious laryngitis in childrenClinical effectAdverse drug reactions
万方数据
维普
