The effect of suture type on the therapeutic effect of minimally invasive repair surgery for patients with perforation of gastroduodenal ulcer
Objective To study the effect of suture type on the therapeutic effect of minimally invasive repair surgery for patients with perforation of gastroduodenal ulcer.Methods A total of 78 patients with perforation of gastroduodenal ulcer were selected,and were randomly divided into an observation group and a control group using a random number table method,with 39 cases in each group.Both groups underwent minimally invasive surgical repair,with 2-0 polyglycolic acid absorbable surgical suture used in the observation group,and 2-0 ordinary silk thread in the control group.The ulcer healing rate,surgical and clinical indicators,postoperative pain intensity,intestinal barrier function,incidence of complications,and quality of life between two groups.Results The ulcer healing rate was 97.44%in the observation group and 74.36%in the control group,and the difference in ulcer healing rates between the two groups was statistically significant(P<0.05).The postoperative pain intensity in the observation group was grade 1 in 17 cases,grade 2 in 19 cases,grade 3 in 2 cases,and grade 4 in 1 case;the postoperative pain intensity in the control group was grade 1 in 9 cases,grade 2 in 18 cases,grade 3 in 8 cases,and grade 4 in 4 cases.There was significant difference in postoperative pain intensity between the two groups(P<0.05).The incidence of complications in the observation group was 2.56%,which was lower than 20.51%in the control group,and the difference was statistically significant(P<0.05).The operation time of the observation group was not significantly different from that of the control group(P>0.05).The time of getting out of bed,time for intestinal function recovery and length of hospital stay in the observation group were(2.26±0.76),(2.54±0.97)and(6.56±1.31)d,which were shorter than(2.85±1.01),(3.18±1.15)and(7.19±1.47)d in the control group(P<0.05).At 3 d after surgery,the serum diamine oxidase(DAO)in the observation group was(118.42±8.46)U/ml and the D-lactic acid(D-Lac)was(23.19±2.08)μg/ml,which were lower than(139.53±9.85)U/ml and(29.47±2.77)μg/ml in the control group(P<0.05).At 8 weeks after surgery,the gastrointestinal quality of life index(GIQLI)score of the observation group was(125.45±9.65)points,which was higher than(107.91±8.37)points of the control group(P<0.05).Conclusion The use of polyglycolic acid absorbable surgical suture in minimally invasive repair surgery for perforation of gastroduodenal ulcer can promote ulcer healing,improve patient's quality of life,and significantly reduce the risk of postoperative complications,and has little effect on intestinal barrier function.
Perforation of gastroduodenal ulcerSuture typePolyglycolic acid absorbable surgical sutureMinimally invasive repair surgery
万方数据
维普
