Study on the clinical prevention and treatment of Peiyuan Shunqi Paste combined with Baduanjin in stable chronic obstructive pulmonary disease
Objective To discuss the clinical efficacy and safety of Peiyuan Shunqi Paste combined with Baduanjin in the treatment of stable chronic obstructive pulmonary disease(COPD).Methods 60 patients with stable COPD were divided into a control group and an observation group according to random number table,with 30 cases in each group.The control group was treated with salmeterol xinafoate and fluticasone propionate aerosol(trade name:Seretide)inhalation alone,and the treatment group was treated with Peiyuan Shunqi Paste and Baduanjin on the basis of the control group.Both groups were compared in terms of traditional Chinese medicine syndrome score,modified medical British research council(mMRC)score,COPD Asessment Test(CAT)score,6-min walking distance,lung function indicators[forced expiratory volume in one second as a percentage to the predicted value(FEV1%),ratio of forced expiratory volume in one second to forced vital capacity(FEV1/FVC)],the blood gas indicators[arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2)],the clinical efficacy,and the occurrence of adverse reactions.Results After treatment,the traditional Chinese medicine syndrome score,mMRC score and CAT score in both groups were lower than those before treatment;and the traditional Chinese medicine syndrome score,mMRC score and CAT score in the observation group were(6.10±0.50),(0.64±0.12)and(9.06±1.14)points,which were significantly lower than(12.50±1.60),(1.06±0.16)and(13.33±1.88)points in the control group(P<0.05).After treatment,the 6-min walking distance,FEV1%,FEV1/FVC and PaO2 in both groups were all higher than those before treatment,and PaCO2 was lower than that before treatment;the observation group had 6-min walking distance of(433.35±50.25)m,FEV1%of(61.85±6.55)%,FEV1/FVC of(70.42±6.23)%,PaO2 of(89.35±7.07)mm Hg(1 mm Hg=0.133 kPa),which were higher than(384.80±48.60)m,(55.64±6.30)%,(65.26±6.33)%,(79.34±7.06)mm Hg in the control group;the observation had lower PaCO2 of(42.02±5.55)mm Hg than(56.12±5.23)mm Hg in the control group(P<0.05).The total effective rate was 93.33%in the observation group,which was higher than 73.33%in the control group(χ2=4.320,P<0.05).No obvious adverse reactions were observed in both groups during treatment.Conclusion Peiyuan Shunqi Paste combined with Baduanjin is a safe,reliable,effective and simple treatment for stable COPD.It can effectively relieve clinical symptoms,improve lung function index and blood gas index,and improve exercise endurance.