metallo-β-lactamase(MBLs)-producing gram-negative bacteria are common pathogens of clinical infection,which can cause a variety of serious infections,among which metallo-β-lactamase-producing Klebsiella pneumoniae(KP)is an important hospital-acquired infection in the world,posing a serious threat to the current anti-infective treatment.As a new cephalosporin,cefiderocol has the characteristics of strong antibacterial activity,wide range of action,strong tissue penetration,etc.It has strong antibacterial activity against carbapenemases-producing enterobacter,Acinetobacter baumannii,pseudomonas aeruginosa,stenomonas maltophilia,and it also has quite good activity against metallo-β-lactamase.In this study,the effect of cefiderocol on metallo-β-lactamase producing gram-negative bacteria is analyzed comprehensively.
关键词
头孢地尔/产金属酶革兰阴性菌/耐药性/临床作用/研究现状
Key words
Cefiderocol/Metallo-β-lactamase-producing gram-negative bacteria/Drug resistance/Clinical effect/Research status
维普
万方数据