Effects of Wenxin granule combined with ivabradine on hemodynamics and electrocardiogram results in elderly patients with ischemic arrhythmia
Objective To investigate the effects of Wenxin granule combined with ivabradine on hemodynamics and electrocardiogram results in elderly patients with ischemic arrhythmia.Methods A total of 172 elderly patients with ischemic arrhythmia were selected as research subjects.According to the principle of random number table,the patients were divided into a control group and a combination group,with 86 cases in each group.Patients in both groups received basic treatment,on this basis,patients in the control group received ivabradine treatment,and patients in the combination group received Wenxin granule combined with ivabradine treatment.The short-term efficacy,hemodynamic indexes[plasma viscosity(PV),erythrocyte sedimentation rate(ESR),hematocrit(HCT)]and electrocardiogram results[heart rate(HR),correct QT(QTc),QT interval dispersion(QTd)]were compared between the two groups.Results At 3 months after treatment,the total effective rate of the combination group was 100.00%,which was higher than 95.35%of the control group,and the difference was statistically significant(P<0.05).At 3 months after treatment,the levels of PV,ESR and HCT in both groups were lower than those before treatment;the combination group had PV of(1.42±0.18)mPa·s,ESR of(16.40±2.81)mm/h and HCT of(40.14±5.33)%,which were lower than(1.69±0.24)mPa·s,(19.55±2.76)mm/h and(45.08±5.64)%in the control group;the difference was statistically significant(P<0.05).At 3 months after treatment,HR,QTc and QTd in both groups were lower than those before treatment;the combination group had HR of(83.20±9.65)beats/min,QTc of(330.64±50.16)ms and QTd of(49.85±6.21)ms,which were lower than(90.64±12.18)beats/min,(371.20±54.58)ms and(57.02±7.44)ms in the control group;the difference was statistically significant(P<0.05).Conclusion The combination of Wenxin granules and ivabradine for elderly patients with ischemic arrhythmia can effectively improve the short-term efficacy,hemodynamics and electrocardiogram results,which is worthy of clinical promotion.
Ischemic arrhythmia in the elderlyWenxin granuleIvabradineHemodynamicsElectrocardiogram
万方数据
维普
