Clinical efficacy of Zaoren Anshen capsule combined with zolpidem tartrate on insomnia patients
Objective To analyze the effect of Zaoren Anshen capsule combined with zolpidem tartrate on insomnia patients.Methods A total of 88 patients with insomnia were studied and randomly divided into the conventional group and the study group,with 44 cases in each group.The conventional group was treated with zolpidem tartrate tablets,while the study group was treated with Zaoren Anshen capsule and zolpidem tartrate tablets.The therapeutic effect,negative emotion score,sleep quality score,traditional Chinese medicine syndrome score and mental health score were compared between the two groups.Results The total effective rate was 81.82%in the conventional group and 97.73%in the study group.Compared with the conventional group,the total effective rate of the study group was higher(P<0.05).Before treatment,there were no significant differences in scores of anxiety and depression between the two groups(P>0.05).After treatment,the scores of anxiety and depression were(53.73±3.31)and(51.88±2.95)points in the conventional group,and(42.03±1.46)and(45.15±0.68)points in the study group,respectively.After treatment,the scores of anxiety and depression in the study group were lower than those in the conventional group,and there were significant differences between the groups(P<0.05).Before treatment,there were no significant differences in scores of subjective sleep quality,daytime dysfunction,sleep time,sleep latency,dreaminess and night wakening between the two groups(P>0.05).After treatment,the scores of subjective sleep quality,daytime dysfunction,sleep time,sleep latency,dreaminess and night awakening in the conventional group were(1.68±0.57),(1.12±0.28),(1.22±0.11),(1.38±0.54),(1.33±1.21)and(1.45±0.52)points,and those of the study group were(1.12±0.24),(0.75±0.24),(0.98±0.27),(0.51±0.16),(0.61±0.04)and(0.94±0.41)points.The scores of subjective sleep quality,daytime dysfunction,sleep time,sleep latency,dreaminess and night awakening in the study group were lower than those in the conventional group(P<0.05).Before treatment,there were no significant differences in traditional Chinese medicine syndrome score and mental health score between the two groups(P>0.05).After treatment,the traditional Chinese medicine syndrome score and mental health score in the study group were(0.51±0.44)and(138.67±16.14)points,and those in the conventional group were(1.39±0.47)and(165.54±14.58)points.The study group was lower than the conventional group(P<0.05).Conclusion Zaoren Anshen capsule combined with zolpidem tartrate for insomnia patients can improve the sleep quality,reduce the negative mood of patients.Compared with zolpidem tartrate tablets alone,the efficacy is higher,and the clinical application value is higher.