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妊娠高血压检验中尿微量白蛋白的诊断价值

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目的 分析妊娠高血压检验中尿微量白蛋白(U-MA)的诊断价值。方法 选取本院 30 例妊娠高血压患者作为观察组,选取 30 例健康妊娠体检者作为对照组。两组均予以血清胱抑素C(Cys-C)、尿β2 微球蛋白(β2-MG)、U-MA检测,并对观察组患者予以综合治疗。比较两组Cys-C、β2-MG、U-MA水平,观察组治疗前后Cys-C、β2-MG、U-MA水平。结果 观察组Cys-C、β2-MG、U-MA水平分别为(3。41±0。34)、(3。67±0。19)、(17。72±2。27)mg/L,均高于对照组的(1。10±0。27)、(1。18±0。10)、(6。26±0。51)mg/L,统计学意义显著(P<0。05)。观察组治疗后Cys-C、β2-MG、U-MA水平分别为(1。12±0。23)、(1。25±0。12)、(6。35±0。65)mg/L,均低于治疗前的(3。41±0。34)、(3。67±0。19)、(17。72±2。27)mg/L,统计学意义显著(P<0。05)。结论 U-MA、Cys-C、β2-MG等指标可作为妊娠高血压早期肾损伤诊断的主要参考指标,与健康妊娠者相比,妊娠高血压患者U-MA等水平明显升高,因此,应及早采取治疗措施,保证母婴健康。
Diagnostic value of urinary microalbumin in pregnancy-induced hypertension
Objective To analyze the diagnostic value of urinary microalbumin(U-MA)in pregnancy-induced hypertension.Methods 30 patients with pregnancy-induced hypertension were selected as the observation group,and 30 healthy pregnant women of physical examination were selected as the control group.Serum cystatin C(Cys-C),urinary β2 microglobulin(β2-MG)and U-MA were detected in both groups,and the observation group was given comprehensive treatment.The levels of Cys-C,β2-MG and U-MA in the two groups were compared,as well as the levels of Cys-C,β2-MG and U-MA in the observation group before and after treatment.Results The levels of Cys-C,β2-MG and U-MA in the observation group were(3.41±0.34),(3.67±0.19)and(17.72±2.27)mg/L,which were higher than(1.10±0.27),(1.18±0.10)and(6.26±0.51)mg/L in the control group,with statistical significance(P<0.05).In the observation group,the levels of Cys-C,β2-MG and U-MA were(1.12±0.23),(1.25±0.12)and(6.35±0.65)mg/L after treatment,which were lower than(3.41±0.34),(3.67±0.19)and(17.72±2.27)mg/L before treatment,with statistical significance(P<0.05).Conclusion U-MA,Cys-C,β2-MG and other indicators can be used as the main reference indicators for the diagnosis of early renal injury in pregnancy-induced hypertension.Compared with healthy pregnant women,U-MA and other levels in patients with pregnancy-induced hypertension are significantly increased.Therefore,early treatment measures should be taken to ensure the health of mother and infant.

Pregnancy-induced hypertensionUrinary microalbuminSerum cystatin CUrinary β2 microglobulinEarly renal injury

廖继梅、钟国华

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404604 重庆市奉节县兴隆镇中心卫生院

妊娠高血压 尿微量白蛋白 血清胱抑素C 尿β2微球蛋白 早期肾损伤

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(5)
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