Observation on clinical effect of dezocine and remifentanil combined with propofol on anesthesia for painless induced abortion
Objective To explore the clinical effect of dezocine and remifentanil combined with propofol on anesthesia for painless induced abortion.Methods 62 patients who received painless induced abortion were randomly divided into a control group and an observation group,with 31 cases in each group.The control group was anesthetized with remifentanil and propofol,while the observation group was anesthetized with dezocine and propofol.Comparison was made on postoperative indicatros[numerical rating scale(NRS)score,recovery time of orientation,recovery time of consciousness],anesthetic effect,hemodynamic indicators[heart rate(HR),mean arterial pressure(MAP),blood oxygen saturation(SpO2)]and adverse reactions between the two groups.Results The NRS score of(2.01±0.53)points in the observation group was lower than(3.11±0.64)points in the control group(P<0.05).There was no statistically significant difference(P>0.05)in the recovery time of orientation and consciousness between the observation group and the control group(P>0.05).In the observation group,the anesthesia effect was grade Ⅰ in 27 cases(87.10%),grade Ⅱ in 3 cases(9.68%),and grade Ⅲ in 1 case(3.23%).In the control group,the anesthesia effect was grade Ⅰ in 20 cases(64.52%),grade Ⅱ in 6 cases(19.35%),and grade Ⅲ in 5 cases(16.13%).The anesthetic effect of the observation group was better than that of the control group(Z=2.125,P=0.034<0.05).During surgery,HR,MAP and SpO2 in the observation group were(77.21±0.51)beats/min,(79.71±0.32)mm Hg(1 mm Hg= 0.133 kPa)and(98.71±0.32)%,which were higher than(70.22±0.25)beats/min,(77.29±0.61)mm Hg and(95.29±0.13)%in the control group(P<0.05).The incidence of adverse reactions in the observation group was 6.45%,which was lower than 25.81%in the control group(χ2=4.292,P=0.038<0.05).Conclusion Compared with remifentanil combined with propofol,diazocin combined with propofol has better overall anesthesia effect for painless induced abortion,can control adverse reactions,and is optional.
万方数据
维普
